نتایج جستجو برای: glycosylated protein

تعداد نتایج: 1244008  

2015
Hui Sun Lee Yifei Qi Wonpil Im

N-linked glycosylation is one of the most important, chemically complex, and ubiquitous post-translational modifications in all eukaryotes. The N-glycans that are covalently linked to proteins are involved in numerous biological processes. There is considerable interest in developments of general approaches to predict the structural consequences of site-specific glycosylation and to understand ...

Journal: :Computational biology and chemistry 2011
R. Shyama Prasad Rao Ole Thomsen Buus Bernd Wollenweber

N-glycosylation is a common protein modification process, which affects a number of properties of proteins. Little is known about the distribution of N-glycosylation sequons, for example, the distance between glycosylated sites and their position in the protein primary sequence. Using a large set of experimentally confirmed eukaryotic N-glycoproteins we analyzed the relative position and distri...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2002
Shunsuke Aoki Qingning Su Hang Li Kaori Nishikawa Kohichi Ayukawa Yoko Hara Kazuhiko Namikawa Sumiko Kiryu-Seo Hiroshi Kiyama Keiji Wada

We developed a new method, designated N-linked glycosylation signal (NGS) differential display (DD)-PCR, that enables the identification of genes encoding N-linked glycosylated molecules that exhibit varying patterns of expression. Using this innovative technique, we identified an N-linked glycosylated 11-transmembrane domain protein that is upregulated in response to axotomy. Expression levels...

2008
Paula Turkki

The melanoma differentiation associated gene-7 (mda-7), also known as interleukin-24 (IL-24) is a novel cytokine, which exhibits both tumor suppressing and immunostimulatory activities. Mda-7 has the ability to restrain growth and induce programmed cell death (apoptosis) in a wide variety of human cancer cells without having similar effects on normal cells. This study was performed to investiga...

Journal: :Gut 2001
J I Semple J L Newton B R Westley F E May

BACKGROUND TFF2, a member of the trefoil factor family of proteins, is a glycosylated protein of 106 amino acids. It is secreted by gastric antral and pyloric glands and by Brunner's glands of the duodenum. TFF2 is found in high concentrations around sites of ulceration. It stimulates cell motility and is probably the principal cytoprotective trefoil peptide in the stomach. AIMS To determine ...

Journal: :The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 1999

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