نتایج جستجو برای: gnrha long protocol

تعداد نتایج: 1006411  

Journal: :European journal of endocrinology 2010
Valentina Chiavaroli Marco Liberati Francesco D'Antonio Fabio Masuccio Rita Capanna Alberto Verrotti Francesco Chiarelli Angelika Mohn

OBJECTIVE GNRH analog (GNRHa) therapy has not been supported by beneficial effects on adult stature in girls with early puberty. Furthermore, an increased prevalence of polycystic ovary syndrome (PCOS) has been described in girls treated for central precocious puberty. Women with PCOS are at increased risk of cardiometabolic dysfunctions and infertility. Our aim was to assess GNRHa effectivenes...

2009
Katherine A Lewis Erica A Eugster

In 2007, a hydrogel histrelin implant was approved for the treatment of children with central precocious puberty (CPP). Children with CPP commonly have reduced height potential due to premature closure of the epiphyseal growth plates from exposure to sex steroids. Gonadotropin-releasing hormone analog (GnRHa) treatment halts puberty and allows for improvement of adult height. A hydrogel implant...

2013
E Kirk Neely Lawrence A Silverman Mitchell E Geffner Theodore M Danoff Errol Gould Paul S Thornton

BACKGROUND Gonadotropin-releasing hormone agonist (GnRHa)-stimulated luteinizing hormone (LH) is the standard hormonal assessment for both diagnosis and therapeutic monitoring of children with central precocious puberty (CPP). Use of unstimulated (random) LH levels may be helpful in diagnosis and has gained popularity in monitoring GnRHa therapy despite lack of validation against stimulated val...

2016
Jae Won Yoo Chun Woo Song Han Hyuk Lim

PURPOSE The effects of gonadotropin-releasing hormone agonist (GnRHa) treatment on the energy metabolism in girls with central precocious puberty (CPP) are controversial. We focused the changes and related factors of serum levels of leptin and adiponectin in girls with CPP before and during GnRHa treatment. METHODS Thirty girls with idiopathic CPP were enrolled in the study. Their auxological...

2017
Pınar Çağlar Aytaç Bülent Haydardedeoğlu Halis Özdemir Esra Bulgan Kılıçdağ

OBJECTIVE To evaluate the effects of a gonadotropin releasing hormone agonist (GnRHa) injection prior to embryo transfer on implantation and pregnancy rate. MATERIALS AND METHODS We performed a retrospective analysis of patients undergoing in vitro fertilization (IVF) therapy with and without GnRHa preinstallation into the uterine cavity just before embryo transfer between January 2012 and Ma...

Journal: :Archives of endocrinology and metabolism 2016
Vinícius Nahime Brito Angela Maria Spinola-Castro Cristiane Kochi Cristiane Kopacek Paulo César Alves da Silva Gil Guerra-Júnior

Clinical and laboratory diagnosis and treatment of central precocious puberty (CPP) remain challenging due to lack of standardization. The aim of this revision was to address the diagnostic and therapeutic features of CPP in Brazil based on relevant international literature and availability of the existing therapies in the country. The diagnosis of CPP is based mainly on clinical and biochemica...

Journal: :Endocrinologia japonica 1990
T Uemura K Shirasu H Sakakibara Y Kondo H Minaguchi

In order to determine the changes in the expression of LH beta messenger ribonucleic acid (mRNA) during GnRH agonist (GnRHa) treatment (0.94 mg/28 days), the concentration of the mRNA of LH beta was assessed together with the serum LH concentration, pituitary LH content and LH response to GnRH at various times during long-acting GnRHa treatment in immature female rats. The serum LH concentratio...

2014
Pin Li Yan Li Chung-Lin Yang Mesut Ogrendik.

In the setting of central precocious puberty (CPP), the motivation for hormonal intervention is to help the child to reach a taller adult stature than she would achieve otherwise. While gonadotropin-releasing hormone analogs (GnRHa) constitute an established treatment for improving adult stature in girls presenting with CPP up to age 6 (true precocious puberty), it is not yet clear whether or n...

Journal: :Endocrinology 2005
Xiaoping Luo Li Ding Jingxia Xu R Stan Williams Nasser Chegini

Gene microarray was used to characterize the molecular environment of leiomyoma and matched myometrium during growth and in response to GnRH analog (GnRHa) therapy as well as GnRHa direct action on primary cultures of leiomyoma and myometrial smooth muscle cells (LSMC and MSMC). Unsupervised and supervised analysis of gene expression values and statistical analysis in R programming with a false...

Journal: :Reproductive Biology and Endocrinology : RB&E 2009
Panagiotis Beretsos George A Partsinevelos Eleni Arabatzi Peter Drakakis Depy Mavrogianni Elli Anagnostou Kostas Stefanidis Aris Antsaklis Dimitris Loutradis

BACKGROUND Recently, it has been demonstrated that, in patients down-regulated by GnRH analogues (GnRHa), a short-term pre-treatment with recombinant LH (rLH), prior to recombinant FSH (rFSH) administration, increases the number of small antral follicle prior to FSH stimulation and the yield of normally fertilized embryos. However, no data exist in the literature regarding the potential benefic...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید