background: laboratory bred sand flies are essential for the study of different biological phenomena including the transmis­sion dynamics of leishmania . the aim of the study was to determine the suitable situation for colonization and main­tenance of iranian strain of phlebotomus papatasi at laboratory conditions from an endemic focus of cutaneous leishmani­asis due to leishmania major . metho...

Experimental inoculation of Mycobact erium lepme murium into the golden hamster, first done by Balfour-Jones, produces a generalized infection of slow but progressive evolution, with lesions in various organs (2,4,14,15). The Chinese hamster, however, is apparently not susceptible to this infection (13). Observations on this infection of the hamster have been mainly from the bacteriological poi...

Optical coherence tomography (OCT)/optical Doppler tomography (ODT) provides real-time in vivo high-resolution (10-microm) imaging of tissues and real-time spatially resolved blood flow in microvasculature. Hamster cheek pouches with induced dysplasia and malignancies were imaged with OCT/ODT to assess the potential for application to airway malignancy. In 22 Golden Syrian hamsters, 0.5% 9,10-d...

The cheek pouch of the golden hamster (Meso cricetus aura@us) has been shown to be a favorable transplantation site for a variety of homologous and heterologous malignant tumors, including a few human epidermoid carcinomas and sarcomas (5,10,1@). Sinceaccuratemeasurements oftrans plant volume are possible according to the technic described by Lutz and co-workers, the kinetics of tumor growth an...