BACKGROUND AND PURPOSE Hyperglycemia strongly predicts poor outcome in patients with aneurysmal subarachnoid hemorrhage, but the effect of hyperglycemia management on outcome is unclear. We studied the impact of glycemic control on outcome of patients with aneurysmal subarachnoid hemorrhage. METHODS A prospective intensive care unit database was used to identify 332 patients with hyperglycemi...

Cadmium (Cd) has recently emerged as a major concern not only in environmental toxicology but also in metabolic diseases such as diabetes mellitus and its complications. Conflicting data aside, these studies have not been examined in a clinical population undergoing management as well as possible modulation by the prominent metabolic antagonist of Cd such as zinc (Zn). This study examined the r...

to achieve tight glycemic control in diabetic patients, it may be necessary to introduce insulin therapy much earlier in the disease course. poor glycemic control is a risk factor for the development of diabetic complications. many patients require insulin therapy after several years of disease in order to maintain good glycemic control and prevent complications. but many patients do not receiv...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 objectives: there is an association between viral infection and development of diabetes mellitus. this study aimed to investigate the role of rubella virus, cytomegalovirus and coxsackievirus in patients with type 1 (t1d)and type 2 (t2d) diabetes mellitus in respect to the glycemic control and immune response presented by ...

BACKGROUND Glycemic control is a known modifiable risk factor for diabetic foot disease. Prior attempts to define its relationship with diabetic foot ulcer and Charcot arthropathy fail to account for variability in control and duration of diabetic disease. We developed a novel metric to reflect aggregate disease exposure in a diabetic, termed cumulative glycemic burden. We hypothesized that it ...

BACKGROUND Although there is a growing body of evidence showing that patients with type 2 diabetes mellitus (T2DM) have poor glycemic control in general, it is not clear whether T2DM patients with pre-existing cardiovascular diseases (CVD) are more or less likely to have good glycemic control than patients without pre-existing CVD. Our aim was to examine the degree of glycemic control among T2D...

With the prevalence of obesity increasing in the U.S. and elsewhere, the place of carbohydrates in the diet has recently been under closer examination. This has led to the development of methods for analyzing the effects of dietary carbohydrate. Primary among these methods is the glycemic index, a measure of a food's effect on blood glucose levels, which was initially designed as a method for d...

Hypoglycemia is one of the most important complications of diabetes treatment. The risk of severe hypoglycemia is higher in elderly patients, those having comorbidities such as vascular disease or renal failure, pregnant women and in children with type 1diabetes. Moreover, in type 2 diabetes, progressive insulin deficiency, longer duration of diabetes, and tight glycemic control increase the ri...

Downloa with renal impairment; in this context, AGEs may provide the common pathophysiological link. An increase in AGEs can be determined fundamentally by 2 factors: the existence of chronic hyperglycemia and/or a high degree of oxidative stress (3). Although AGEs occur as a result of hyperglycemia, their effects can occur independently of glycemic control. This finding may explain the paradox...