The mature arenavirus envelope glycoprotein GPC is a tripartite complex comprising a stable signal peptide (SSP) in addition to the receptor-binding (G1) and transmembrane fusion (G2) subunits. We have shown previously that SSP is a key element in GPC-mediated membrane fusion, and that GPC sensitivity to acidic pH is modulated in part through the lysine residue at position 33 in the ectodomain ...

fourier transform infrared (ftir) and gel permeation chromatography (gpc) wre respectively utilized in determining the changes in isocyanate (nco) concentration and molecular weight (mw) and its distribution (mwd) in polyurethanes during their cure and postcure stages. samples, originally cured at 45°c, were taken through accelerate aging tests at various temperatures. the ftir and gpc analytic...

We develop the theory for a robust and efficient adaptive multi-element generalized polynomial chaos (ME-gPC) method for elliptic equations with random coefficients for a moderate number (O(10)) of random dimensions. We employ loworder (p≤ 3) polynomial chaos and refine the solution using adaptivity in the parametric space. We first study the approximation error of ME-gPC and prove its hpconver...

The addition of 1-acyl-sn-glycero-3-phosphocholine (1-acyl-GPC) to peroxisomes decreased the production of acid-soluble radioactivity formed by beta-oxidation of [1-(14)C]arachidonate due to substrate removal by esterification into the acceptor. This peroxisomal-associated acyl-CoA:1-acyl-GPC acyltransferase activity was due to microsomal contamination. The production of acid-soluble radioactiv...

The natural Sri Lanka graphite (vein graphite) is widely-used as anode material for lithium-ion batteries (LIBs), due to its high crystallinity and low cost. In this work, graphitic porous carbon (GPC) and high-purity vein graphite (PVG) were prepared from Sri Lanka graphite ore by KOH activation, and high temperature purification, respectively. Furthermore, a lithium-ion capacitor (LIC) is fab...

We report in this paper that glycophorin C (GPC) is the receptor for PfEBP-2 (baebl, EBA-140), the newly identified erythrocyte binding ligand of Plasmodium falciparum. PfEBP-2 is a member of the Duffy binding-like erythrocyte binding protein (DBL-EBP) family. Although several reports have been published characterizing PfEBP-2, the identity of its erythrocytic receptor was still unknown. Using ...

BACKGROUND In recent years a wide variety of flavonoids or polyphenolic substances have been reported to possess substantial anti-carcinogenic and antimutagenic activities. Grape proanthocyanidins (GPC) are considered as good examples for which there is evidence of potential roles as anti-carcinogenic agents. METHODS A xenograft model was established using H22 cells subcutaneously injected in...

Glycophorin C (GPC) and glycophorin D (GPD) are homologous sialoglycoproteins in the human red blood cell membrane. Both are thought to be encoded by the GPC gene (GYPC). We report that the rare blood group antigen, An", is expressed on GPD but not on GPC. cDNA was synthesized from total RNA obtained from two unrelated, heterozygous Ana+ blood donors and analyzed by the polymerase chain reactio...

We investigate quantile estimation by multi–element generalized Polynomial Chaos (gPC) metamodel where the exact numerical model is approximated by complementary metamodels in overlapping domains that mimic the model’s exact response. The gPC metamodel is constructed by the non–intrusive stochastic spectral projection approach and function evaluation on the gPC metamodel can be considered as es...

A microstructure beam is one of the fundamental elements in MEMS devices like cantilever sensors, RF/optical switches, varactors, resonators, etc. It is still difficult to precisely predict the performance of MEMS beams with the current available simulators due to the inevitable process deviations. Feasible numerical methods are required and can be used to improve the yield and profits of the M...