Computational Grids are much more complex than classical high-performance architectures: they have high, and dynamically varying communication latencies, and comprise heterogeneous collections of processing elements. We argue that such a complex and dynamic architecture is extremely challenging for the programmer to explicitly manage, and advocate a high-level parallel programming language, lik...

Time domain tests of unit roots and cointegration are often made after a model search procedure has been made in order to reduce erroneus inference caused by model misspecification. An alternative to this is to use a semi parametric method like the GPH (Geweke & Porter-Hudak, 1983) test where the properties of the spectral density close to the zero frequency are exploited, see Cheung & Lai (199...

A new family of homologous membrane proteins that transport galactosides-pentoses-hexuronides (GPH) is described. By analysing the aligned amino acid sequences of the GPH family, and by exploiting their different specificities for cations and sugars, we have designed mutations that yield novel insights into the nature of ligand binding sites in membrane proteins. Mutants have been isolated/cons...

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is considered a multifunctional protein with defined functions in numerous mammalian cellular processes. GAPDH functional diversity depends on various factors such as covalent modifications, subcellular localization, oligomeric state and intracellular concentration of substrates or ligands, as well as protein-protein interactions. In bacteria, al...

The human gastrointestinal tract can be positively modulated by dietary supplementation of probiotic bacteria in combination with prebiotic carbohydrates. Here differential transcriptomics and functional genomics were used to identify genes in Lactobacillus acidophilus NCFM involved in the uptake and catabolism of 11 potential prebiotic compounds consisting of α- and β-linked galactosides and g...

We have studied the effect of ingestion of unlimited clear fluids by adolescents up to 3 h before anaesthesia to determine the effect this fluid ingestion would have on thirst, hunger and gastric contents at induction of anaesthesia. We studied prospectively 152 adolescents (ages 13-19 yr) undergoing elective surgery. Fifty percent of the patients had nothing by mouth after midnight. The other ...

The three-dimensional structure of bacteriophage phi X174 (phi X174) was determined to approximately 2.6 nm resolution from images of frozen-hydrated 114 S particles. The outer surface of phi X174 is characterized by several prominent features: (i) 12 mushroom-shaped caps (approximately 7.1 nm wide x 3.8 nm high) are situated at each of the vertices of the icosahedral virion and extend to a max...

Abstract European climate is associated with variability and changes in the mid-latitude atmospheric circulation. In this study, we aim to investigate potential future change circulation over Europe by using EURO-CORDEX regional projections at 0.11° grid mesh. particular, analyze 500-hPa geopotential height (Gph), wind speed mean sea level pressure (MSLP) addressing different warming levels of ...

The design and implementation of useful programming languages , whether sequential or parallel, should be driven by large, realistic applications. In constructing several medium-and large-scale programs in Glasgow Parallel Haskell, GpH, a parallel extension of Haskell, the group at Glasgow has investigated several important engineering issues: { Real Application Parallelism. The programs achiev...

IHPBI is an early indicator in consumer price analysis. When the increases, it results inflation. inflation occurs, Indonesia's economic stability begins to be disturbed, so order suppress inflation, government raises interest rates and when circulation of money decrease, prices goods services will return normal. This research see next 3 years through ARFIMA method multi-input intervention with...