18β-glycyrrhetinic acid (GRA) exerts anti-tumor effects on various types of cancer. In the present study, we found that GRA attenuated the severity of gastritis and suppressed gastric tumorigenesis in transgenic mice. We also discovered that miR-149-3p was downregulated in gastric cancer tissues and cell lines as compared to normal gastric tissues and epithelial cells, but was upregulated by GR...

In the end of 1990’s, Dutch road infrastructure redesign programmer was launched for improving traffic safety. In the mean time the ongoing development in Advanced Driver Assistance Systems (ADAS) seems to offer viable alternatives. These strategies are not only to a large extent substitutes, but also partly complementary. A notorious problem is the ex-ante evaluation of these strategies. This ...

18β-Glycyrrhetinic acid (GRA), a natural immunomodulator, greatly reduced the parasite load in experimental visceral leishmaniasis through nitric oxide (NO) upregulation, proinflammatory cytokine expression, and NF-κB activation. For the GRA-mediated effect, the primary kinase responsible was found to be p38, and analysis of phosphorylation kinetics as well as studies with dominant-negative (DN...

Banking sector is one of the most important factors in development of economy. A strong and healthy banking sector is considered to be a prerequisite for sustainable economic growth. In this study, the aim is to apply Gray Relational Analysis (GRA) to measure and compare financial performances of 10 banks with common stock trading in Istanbul Stock Exchange (ISE) between the years of 2005–2011....

GRA 06128/9: Since their discovery at Graves Nunataks icefield during the 2006/2007 Antarctic Search for Meteorites field season, GRA 06128 and GRA 06129 have received considerable scientific attention. Their elevated modal abundances of oligoclase (>75%), blocky or slab-like character, granoblastic textures and ‘andesitic’ bulk compositions set them apart from all other meteorite classes. It h...

This study investigated the optimization of computer numerical control (CNC) boring operation parameters for aluminum alloy 6061T6 using the grey relational analysis (GRA) method. Nine experimental runs based on an orthogonal array of Taguchi method were performed. The surface properties of roughness average and roughness maximum as well as the roundness were selected as the quality targets. An...

Quantitative and qualitative fuzzy measures have been proposed to hesitant fuzzy sets 9 (HFSs) from different points. However, few of the existing HFSs fuzzy measures refer to the grey 10 relational analysis (GRA) theory. Actually, the GRA theory is very useful in the fuzzy measure 11 domain, which has been developed for such the intuitionistic fuzzy sets. Therefore, in this paper, 12 we apply ...

Me Me M di di dic ca cal l Un Un Univ iv iver er e si si sity ty ty G G Gra ra raz, z, G G Gra ra raz, z, z A A Aus us str tr tria ia ia Abstract Background—Guidelines on neonatal resuscitation recommend 90 chest compressions (CC) and

Introduction: Several studies have contributed to our understanding of the record of alteration of CR chondrites [e.g., 1-5]. However, recent observations of CR2 GRA 06100 suggest that hydration of the CR parent body was a more diverse process than previously anticipated [6]. [6] observed that Fe,Ni metal in this meteorite was invariably and extensively altered to form complex assemblages conta...