OBJECTIVES To compare the efficacy and safety of thymoglobulin compared with basiliximab in patients who had kidney transplants and are at high risk for acute rejection and delayed graft function. MATERIALS AND METHODS A retrospective review of patients who had 1 or more risk factors for acute rejection and delayed graft function and who were given either thymoglobulin or basiliximab for indu...

BACKGROUND AND OBJECTIVE The demand for kidney transplants exceeds the existing supply. This leads to a recently growing interest of research in the area of factors that could prolong graft long-term outcomes and survival. In Lithuania, approximately 90% of kidney transplantations are from deceased donors. Donor organs are received and shared only inside the country territory in Lithuania; ther...

Objective: to determine the efficacy and safety of an integrated strategy aimed at preventing delayed renal graft function (DGF). Materials methods . From June 2018 December 2022, 478 deceased-donor kidney transplants were performed Botkin Hospital, Moscow. The patients divided into two groups: Group I consisted 128 who did not use strategy; II included 67 in whom DGF prevention was used periop...

BACKGROUND Suboptimal early graft function following renal transplantation remains a significant challenge. It is suggested that clinical variables (or scoring systems based thereon) may predict the occurrence of delayed graft function (DGF), defined as post-operative dialysis requirement. However, data is conflicting, and suboptimal renal function not requiring dialysis has been little investi...

Background: Saline is still the most widely used storage and rinsing solution for vessel grafts during cardiac surgery despite knowing evidence of its negative influence on human endothelial cell function. Aim this study was to assess effect DuraGraft©, an intraoperative graft treatment solution, saphenous vein segments further elaborate vasoprotective rat aortic in comparison saline. Methods: ...