Granulomatous disorders include a wide variety of infectious and non-infectious conditions with heterogeneous clinical courses considerable constraints affected organs. We take cutaneous sarcoidosis as model disease to acquire new insights into the pathomechanisms granulomas. combined single-cell high-dimensional spatial transcriptomics fluorescently labeled antibody detection for protein expre...

INTRODUCTON: Many lesions of the jaws contain giant cells, they include Peripheral giant cell granuloma, Central giant cell granuloma, aneurismal bone cyst, brown tumor of hyperparathyroidism and early stage of cherubism. Giant cell granuloma which is a benign bone lesion that occurs mainly in the jaws are not tumor but tumor like conditions, the cause of tumor like condition is chronic truma w...

in patients with malignancy, the common etiologies of granuloma formation are tumor related sarcoid reaction, sarcoidosis, tuberculosis and other granulomatous diseases. often, the finding of granulomas in malignant patients may obscure the primary malignancy or may mislead towards treatment of infectious and other etiologies. hence, their proper recognition and necessary follow up is needed to...

STATEMENT OF THE PROBLEM Peripheral and central giant cell granuloma are two common benign lesions of the oral cavity. In spite of histopathological similarities, they have different clinical behaviors. Cathepsin D is a lysosomal enzyme which has different functions on the basis of protein and applied peptide cleavage. PURPOSE This research aimed to evaluate and compare the expression level o...

Der vorliegende Aufsatz setzt sich mit der Problematik Zauberflöte auseinander, deren Libretto im Hinblick auf Szenen und Situationen untersucht wird, in denen die Frage des menschlichen Gesichts aufgegriffen wird. Es geht erster Linie darum, Physiognomik zurückgehenden Inspirationen Textbuch Oper zu ermitteln den hier gehandhabten Umgang Bildlichkeit unter Bezugnahme kulturwissenschaftliche Er...

Pyogenic granuloma or granuloma pyogenicum is a well-known oral lesion. The name pyogenic granuloma is a misnomer since the condition is not associated with pus and does not represent a granuloma histologically. Pyogenic granuloma of the oral cavity is known to involve the gingiva commonly. Extragingivally, it can occur on the lips, tongue, buccal mucosa, palate, and the like. A history of trau...

Granulomas are classified as immune or foreign body granulomas. Of these, the immune granulomas, a hallmark of granulomatous inflammation, are closely related to cell-mediated immune responses. The aim of the present study is to characterize immune granuloma cells in 33 patients with granulomatous inflammation focusing on the expression of CD205 (DEC205), a cell surface marker of antigen presen...