d-tartaric acid is successfully used as a green and efficient catalyst for the synthesis of 3,4-dihydropyrimidin-2(1h)-ones under solvent-free conditions. the developed method has many advantages, including devoid of harmful catalyst and solvents, high yield and easily work-up.

a mild and efficient one-pot three-component and environmentally benign approach for the synthesis of a wide range of hydantoin annulated derivatives has been described. a multi-component reaction between a carbonyl compounds (ketone or aldehyde), potassium cyanide and ammonium carbonate (as cyanating agent and amine source, respectively leads to the formation of hydantoins. the proposed optimi...

A green and efficient protocol for the synthesis of 3,3,6,6-tetramethyl-9-aryl-1,8-dioxooctahydroxanthene derivatives via cyclocondensation of 5,5-dimethyl-1,3-cyclohexanedione and aromatic aldehydes in the presence of catalytic amount of 10-molybdo-2-vanadophosphoric acid under solvent-free conditions has been described. The 10-molybdo-2-vanadophosphoric acid was prepared and characterized by ...

The catalytic highly regio-, diastereo-, and enantioselective synthesis of a small library of spiropyrrolizidineoxindolesvia a four-component 1,3-dipolar cycloaddition reaction of azomethine ylides, derived from isatin, with electron-deficient dipolarophilewas described. The process occurs at room temperature in aqueous ethanol as a green solvent and in the presence of a bidendatebis(imine)–Cu(...

A green and efficient protocol for the synthesis of 3,3,6,6-tetramethyl-9-aryl-1,8-dioxooctahydroxanthene derivatives via cyclocondensation of 5,5-dimethyl-1,3-cyclohexanedione and aromatic aldehydes in the presence of catalytic amount of 10-molybdo-2-vanadophosphoric acid under solvent-free conditions has been described. The 10-molybdo-2-vanadophosphoric acid was prepared and characterized by ...

A friendly benign, green, rapid and facile strategy for synthesis a series of arylquinoxalines was achieved by condensation of aromatic 1,2-diamines with arylglyoxals under clay-catalyzed as an inexpensive and eco-friendly catalyst using grindstone chemistry. Significant decreases in reaction times and high yields have been observed by this green chemistry approach in comparison with previously...

Due to the vast importance of peptides in biological processes, there is an escalating need for synthetic peptides to be used in a wide variety of applications. However, the consumption of organic solvent is extremely large in chemical peptide syntheses because of the multiple condensation steps in organic solvents. That is, the current synthesis method is not environmentally friendly. From the...

The reaction of pyrrole-2-carboxaldehyde and 2-(methyl-sulfan-yl)aniline in refluxing methanol gave an olive-green residue in which yellow crystals of the title compound, C12H12N2S·CH3OH, were grown from slow evaporation of methanol at 263 K. In the crystal, hydrogen-bonding inter-actions link the aniline mol-ecule and a nearby methanol solvent mol-ecule. These units are linked by a pair of wea...

in this researchsaccharomyces cerevisiae (baker’s yeast) was used as a cheap, readily accessible, selective, efficient, and green bio-catalyst in a chemo selective reduction of carbonyl group to hydroxyl group. in this green procedure three substrates e.g. (3-(3-nitrophenyl)aziridin-2-yl)-1-phenyl-methanone, pyruvate ester, and 2-acetyl-γ-butyrolactone were reduced to their corresponding reduce...