Centella asiatica (L.) Urb. is one of the important medicinal and nutraceutical herbs being used by ethnic people since prehistoric times. It accumulates large amount of pentacyclic triterpenoid saponins which forms the major store house of secondary metabolites providing active compounds stimulating cell rejuvenation, improving physical and mental health. C. asiatica also serves dietetic purpo...

Centella asiatica extract is a rich source of natural bioactive substances, triterpenoid saponins, flavonoids, phenolic acids, triterpenic steroids, amino acids and sugars. Thus, many scavenging free radicals, exhibit antiinflammatory activity and affect on the stratum corneum hydration and epidermal barrier function. The aim of the present study was to evaluate the in vivo moisturizing and ant...

Titrated Extract of Centella Asiatica (TECA) is a reconstituted mixture of three triterpenes extracted from the plant and is being used in Europe in wound healing drugs. TECA has been shown to stimulate collagen synthesis in fibroblast cultures and to increase the tensile strength of tissues. Centella asiatica (also known as gotu kola, tiger grass and indian pennywort) is a perennial creeping p...

We aimed to assess the efficacy of Centella asiatica for improvement of the signs and symptoms of chronic venous insufficiency (CVI). We searched 13 electronic databases including the Cochrane Central Register of Controlled Trials for randomised controlled trials assessing the efficacy of Centella asiatica for CVI. Two review authors independently selected studies, assessed the risks of bias of...

In this study the effect of Centella asiatica L. extract was studied against genotoxic doses of ethinylestradiol on human lymphocytes culture. The different doses of C. asiatica L. extract i.e. 1.075x10-4, 2.125x10-4 and 3.15x10-4 g/ml were treated separately with 5 μM of ethinylestradiol. Similar treatments were given with 10 μM of ethinylestradiol. The treatments result in a significant dose ...

Plants have been demonstrated extraordinary source of medicine, and recently focus on medicinal plant research has increased. Centella asiatica is well known for its traditional uses and medicinal properties for the treatment of many diseases. The published literatures mention the use of this plant as whole and bioactive compounds isolated are widely used in the treatment of various human ailme...

Fruits of Berberis asiatica and Pyracantha crenulata are traditionally consumed by local people of north western Himalayan states of India for the treatment of oxidative stress induced ailments. Methanolic extract from mature fruits were evaluated for their total phenolics, related antioxidant compounds and activities. Result showed that Berberis asiatica possesses the higher level of total pol...

In the present study the effect of Centella asiatica L. extract was studied against the genotoxic doses of ethinylestradiol on human lymphocytes culture. The different doses of C. asiatica L. extract i.e. 1.075×10 -4 , 2.125×10 -4 and 3.15×10 -4 g/ml were treated separately with 5 μM of ethinylestradiol. Similar treatments were given with 10 μM of ethinylestradiol. The treatments result in a si...

The present research was planned to characterize the aroma composition of important members of the Lamiaceae family such as Salvia officinalis, Lavandula angustifolia and Mentha asiatica. Aroma components of the S. officinalis, L. angustifolia and M. asiatica were extracted with the purge and trap technique with dichloromethane and analyzed with the gas chromatography-mass spectrometry (GC-MS) ...

BACKGROUND Centella asiatica (C. asiatica) was previously reported to have anti-hyperglycemic effects in animal diabetic model rats. However, its activity on organ and tissue level remains unstudied. Our study aims at exploring the possible effects, C. asiatica extract and insoluble fiber has on carbohydrate absorption, insulin secretion, insulin sensitivity and glucose utilization. METHODS F...