نتایج جستجو برای: growth differentiation factor 9b gdf9b

تعداد نتایج: 1620112  

Journal: :Developmental Immunology 1998
Claudia S. Freitas Sergio R. Dalmau Karla Kovary Wilson Savino

In the present study, we used the fetal organ culture (FTOC) technique in order to study a putative effect of epidermal growth factor (EGF) on the thymus ontogeny. Functional EGF receptors and more recently the EGF molecule itself, respectively, on the membrane of epithelial components of thymic stroma and on a few thymocytes in adult thymus, had been reported in the literature. We could observ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1988
H Matsuda M D Coughlin J Bienenstock J A Denburg

Nerve growth factor (NGF) is a neurotropic polypeptide necessary for the survival and growth of some central neurons, as well as sensory afferent and sympathetic neurons. Much is now known of the structural and functional characteristics of NGF, whose gene has recently been cloned. Since it is synthesized in largest amounts by the male mouse submandibular gland, its role exclusively in nerve gr...

Journal: :Anais da Academia Brasileira de Ciencias 2009
Telma T Schwindt Fabiana L Motta Barnabé Gabriela F Massant Cristina G Alessander O Guimarães Maria Elisa Calcagnotto João B Pesquero Luiz E Mello

Cell therapy for neurological disorders has advanced, and neural precursor cells (NPC) may become the ideal candidates for neural transplantation in a wide range of diseases. However, additional work has to be done to determine either the ideal culture environment for NPC expansion in vitro, without altering their plasticity, or the FGF-2 and EGF mechanisms of cell signaling in neurospheres gro...

Mohammadreza Alijani, Moosa Javdani, Rasool Rahimi Junqani,

Spinal cord injury (SCI) is a neurologic disorder that have a significant impact on quality of life, life expectancy, and economic burden. SCI leads to irreversible neuronal loss and ultimately leads to paralysis. Mesenchymal stem cells (MSCs) are a promising source for cellular therapy because they have possessed the capacity of self-renewal and differentiation to several distinct mesenchymal ...

Background and Objectives: The mesenchymal stem cells derived from peripheral blood (PB) have been recognized as a promising source for allogeneic cell therapy. The aim of this study was to investigate the isolation, growth and differentiation ability of peripheral blood-isolated mesenchymal stem cells. Methods: The mononuclear cells were purified from fr...

Journal: :Journal of the American Society of Nephrology 2017

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