نتایج جستجو برای: gut tissue

تعداد نتایج: 959360  

Journal: :Frontiers in Bioengineering and Biotechnology 2020

Journal: :Journal of Pathology and Translational Medicine 2020

Journal: :Current Opinion in Physiology 2021

Gastrointestinal pathogens employ a variety of mechanisms to damage host tissue, acquire nutrients, and evade treatment. To supplement broad-spectrum antimicrobials, there has been increasing interest in designing molecules that target specific taxa virulence processes. Excitingly, these antivirulence therapies may be able synthesized by gut-resident microbes, thereby enabling delivery drugs di...

Journal: :The Journal of nutrition 2000
N M Delzenne N Kok P Deloyer G Dandrifosse

Nondigestible but fermentable dietary fructans such as oligofructose exert many effects on gut physiology through their fermentation end products such as short-chain fatty acids. Could other metabolites be produced in the gut and contribute to the physiologic effects of dietary fructans? The aim of the study was to evaluate the influence of oligofructose on putrescine, spermidine and spermine c...

2015
Emmanuel Denou Karine Lolmède Lucile Garidou Celine Pomie Chantal Chabo Trevor C Lau Morgan D Fullerton Giulia Nigro Alexia Zakaroff-Girard Elodie Luche Céline Garret Matteo Serino Jacques Amar Michael Courtney Joseph F Cavallari Brandyn D Henriksbo Nicole G Barra Kevin P Foley Joseph B McPhee Brittany M Duggan Hayley M O'Neill Amanda J Lee Philippe Sansonetti Ali A Ashkar Waliul I Khan Michael G Surette Anne Bouloumié Gregory R Steinberg Rémy Burcelin Jonathan D Schertzer

Pattern recognition receptors link metabolite and bacteria-derived inflammation to insulin resistance during obesity. We demonstrate that NOD2 detection of bacterial cell wall peptidoglycan (PGN) regulates metabolic inflammation and insulin sensitivity. An obesity-promoting high-fat diet (HFD) increased NOD2 in hepatocytes and adipocytes, and NOD2(-/-) mice have increased adipose tissue and liv...

2015
Adil Mardinoglu Saeed Shoaie Mattias Bergentall Pouyan Ghaffari Cheng Zhang Erik Larsson Fredrik Bäckhed Jens Nielsen

The gut microbiota has been proposed as an environmental factor that promotes the progression of metabolic diseases. Here, we investigated how the gut microbiota modulates the global metabolic differences in duodenum, jejunum, ileum, colon, liver, and two white adipose tissue depots obtained from conventionally raised (CONV-R) and germ-free (GF) mice using gene expression data and tissue-specif...

2017
Yugang Huang HouBao Qi Zhiqian Zhang Enlin Wang Huan Yun Hui Yan Xiaomin Su Yingquan Liu Zenzen Tang Yunhuan Gao Wencong Shang Jiang Zhou Tianze Wang Yongzhe Che Yuan Zhang Rongcun Yang

Gut microbiota may not only affect composition of local immune cells but also affect systemic immune cells. However, it is not completely clear how gut microbiota modulate these immune systems. Here, we found that there exist expanded macrophage pools in huREG3γ tgIEC mice. REG3γ-associated Lactobacillus, which is homology to Lactobacillus Taiwanese, could enlarge macrophage pools not only in t...

Journal: :Bulletin of environmental contamination and toxicology 2015
Sambhaji Mote Ranjeet Kumar B G Naik Baban S Ingole

An ecotoxicological study were conducted to evaluate the concentrations of PAHs and n-alkanes, in gut, liver and kidney tissues of two individuals of Enhydrina schistose (Daudin, 1803), using gas chromatography/mass spectrometry. The concentrations of PAHs (0.10 µg/g) and n-alkanes (8.12 µg/g) were elevated in the gut, and liver (PAHs 0.05 µg/g tissue, n-alkanes 29.16 µg/g tissue). In kidney of...

Journal: :Bone 2016
Sity Aishah Mansur Aleksandra Mieczkowska Peter R Flatt Beatrice Bouvard Daniel Chappard Nigel Irwin Guillaume Mabilleau

Obesity and type 2 diabetes mellitus (T2DM) progress worldwide with detrimental effects on several physiological systems including bone tissue mainly by affecting bone quality. Several gut hormones analogues have been proven potent in ameliorating bone quality. In the present study, we used the leptin receptor-deficient db/db mice as a model of obesity and severe T2DM to assess the extent of bo...

Journal: :iranian journal of veterinary research 2014
n. erfani majd m. mayahi a. sadeghi moghadam

this study was conducted because of influence of prebiotics (alphamune) and symbiotic (biomin) on histometrical development of small intestine and lymphatic tissue of caecal tonsil have been not reported on broiler chicken. in this study, different parts of small intestine and caecal tonsil, which is a major area of gut associated lymphatic tissue (galt) in chicken were selected. one hundred an...

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