Chromosome 8p is considered, from loss of heterozygosity analysis, to be a strong candidate for the location of a tumor suppressor gene inactivated in colorectal cancer. We have found a 53% (27 of 51) rate of allelic loss at the LPL locus on 8p22, with the smallest region of overlap of deletions including the region D8S258 to D8S277. Using microcell-mediated monochromosome 8 transfer into three...

This paper studies the effects of asymmetries in re-election probabilities across parties on public policy and its subsequent propagation to the economy. The struggle between opposing groups–that disagree on the composition of public consumption–results in governments being endogenously short-sighted: Systematic under investment in infrastructure and overspending on public goods arise, as resou...

During the 1993 NASA Stratospheric Photochemistry, Aerosols and Dynamics Expedition (SPADE), anomalously low nitric oxide (NO) was found in a distinct sunlit layer located above the mid-latitude tropopause. The presence of a significant amount of reactive nitrogen (NOy) in the layer implies the systematic removal of NO, which is without precedent in stratospheric in situ observations. Large inc...

Infrared predissociation spectroscopy of ion-solvent clusters has allowed us to examine the effects of sequential hydration on the reactivity of cations such as NO, NO2, and protonaled formaldehyde, H2COH, stable gas phase ions which are known to undergo rapid reactions in aqueous solution. Our experiments demonstrate that these ions undergo hydration reactions at critical cluster sizes. The sm...

Solution aerosols are injected into an inductlvety coupled argon plasma (ICP) to generate a relatively high number density of positive ions derived from elemental constituents. A small fraction of these ions is extracted through a sampling orifice into a differentially pumped vacuum system housing an ion lens and quadrupole mass spectrometer. The positive ion mass spectrum obtained during nebul...

Curves as a subject of differential geometry have been intriguing for researchers throughout mathematical history and so they have been one of the interesting research fields. Regular curves play a central role in the theory of curves in differential geometry. In the theory of curves, there are some special curves such as Bertrand curves, Mannheim curves, involute and evolute curves, and pedal ...

examined by measuring Pimax once a week for 4 weeks in 91 patients with chronic obstructive pulmonary disease using an aneroid pressure gauge. Five Pimax trials were conducted at each test. From the first to the fourth test, the Pimax increased by a mean of 9 cm H20 (SD 10). From the third to the fourth test, Pimax increased by a mean of 2 cm H20 and performance appeared to be plateauing. The t...

Individual fluid inclusions in quartz were investigated by synchrotron radiation X-ray fluorescence (SXRF) microprobe to develop protocols for major-element microanalysis. Studies were conducted of synthetic fluid inclusions in Brazilian quartz that contain fluids of known NaC1-CaC12-H20 and KCI-H20 compositions. Inclusions were irradiated by synchrotron X-rays and the resulting energy-dispersi...