The dengue viruses belong to the family Flaviviridae, named after the prototype yellow fever virus, which has played a leading role in the development of the science of medical virology. Other important viruses in this family are the Japanese encephalitis virus, St. Louis encephalitis virus and tick-borne encephalitis virus. All these viruses are arthropod-borne viruses and are important causes...

AIMS To characterise a novel strain of adenovirus (Ad) type Ad8 (genome type Ad8I) involved in an epidemic keratoconjunctivitis (EKC) outbreak in Hiroshima city using serological testing and sequence analysis of the fibre and hexon gene. METHODS A neutralisation test (NT) was performed in microtitre plates containing a confluent monolayer of A549 cells using 100 tissue culture infectious dose...

The aim of this study was to investigate the prevalence of Newcastle Disease in Lafia Local Government Area of Nasarawa State, Nigeria. Five districts were selected which includes; Lafia central, Shabu, Kwandare, Assakio and Agyaragu. A total of 1,250 samples were randomly collected for a period of 18 months (June2011 to November, 2012). Haemagglutination Inhibition (HI) Test was used to analyz...

Lectin from the bulbs of Cyclamen mirabile which is an endemic species Turkey was successfully isolated by affinity precipitation with alginate in one step. The purified protein produced two bands showing a dimeric structure SDS-PAGE (13.5 and 14.8 kDa). C. lectin showed activity stability broad pH scale kept its haemagglutination temperature range 4-40°C. MgCl2 HgCl2 inhibited lectin. In this ...

Immune and non-immune rubella sera were examined in the haemagglutination inhibition (HAI) test to evaluate the removal of lipoprotein non-specific inhibitors (NSI) of haemagglutination after kaolin and manganous chloride/heparin treatments. The sera were titrated fresh or after lipoprotein deterioration brought about by ageing the samples at 4 degrees C for various periods of time and by freez...

According to Nelson (1953), " the immune-adherence phenomenon" is concerned with the specific attachment which occurs between erythrocytes and micro-organisms which are sensitized by antibody (Ab) and Complement (C'). Measurements of immune-adherence (IA) may be performed by counting the Treponema pallida remaining in the fluid phase of reaction mixtures containing T. pallida, Ab, C', and eryth...

An epidemiological study of 36 U.S. Marines living in a barracks and exposed to infectious hepatitis was made, and the ability of their sera to agglutinate day-old chick erythrocytes was found to be abnormally high in 52.8% of the group. The other groups of American Servicemen similarly exposed showed no such deviation from the normally expected incidence of raised titres. An unexplained, abnor...

background and aims: vaccine is available, but fetal infection with rubella virus is still a main cause of congenital birth defects and mental retardation in many countries. mass vaccination campaigns and expanded program of immunization (epi) have increased vaccine coverage in the world with a substantial impact on the reduction of rubella infections, such as congenital rubella syndrome (crs)....