the structural requirements for the inhibitor activity of various furan carboxanilide derivatives against succinate dehydrogenase complex (sdc) activity in mitochondria of either wild or mutant strains of ustilago maydis were investigated with the aid of hansch qsar analysis. it has been found that the inhibitor activity against both types of enzymes is best related to the ??? or ??m of the sub...

stability of the π-π stacking interactions in the ben||substituted-coronene and hfben||substituted-coronene complexes was studied using the computational quantum chemistry methods (where ben and hfben are benzene and hexaflourobenzene, || denotes π-π stacking interaction, substituted-coronene is coronene molecule which substituted with four x groups, and x= nh2, ch3, oh, h, f, cf3, cn and no). ...

The influence of aqueous halide solutions on collagen coatings was tested. The effects on resistance against indentation/penetration on adhesion forces were measured by atomic force microscopy (AFM) and the change of Young's modulus of the coating was derived. Comparative measurements over time were conducted with halide solutions of various concentrations. Physical properties of the mesh-like ...

S-Adenosylhomocysteine (AdoHcy) hydrolase is irreversibly inactivated by (E)-5',6'-didehydro-6'-deoxy-6'-halohomoadenosines (EDDHHAs, halogen = I, Br, and Cl). The inactivation is concomitant with the reduction of the enzyme-bound NAD+ (E.NAD+) to NADH, the release of halide ion, and the formation of adenine (Ade) from the EDDHHAs. The mechanism of this inactivation involves two catalytic pathw...

The binding mechanism of the interactions of halide ions (F, Br and I) with bovine serum albumin (BSA) and hemoglobin (Hb) were studied at different temperatures, by using ion-selective electrodes. The experimental data were treated according to Klotz equation, and the number of binding sites and the binding constants were determined. The results show that the binding sites of F on protein mole...

In the present work the effect of different concentration of halide quenchers (Cl, Br, I) on 4-methyl-5-ethoxy-7-methoxy coumarin (1) and 4-methyl-5,7-diethoxy coumarin (2) in aqueous solutions have been carried out at 20 temperature. It was observed that the fluorescence intensity of these coumarin derivatives decrease with increase in the concentration of the quenchers except Cl quencher. Fur...

Haloalkane dehalogenase from Xanthobacter autotrophicus GJ10 catalyzes the conversion of 1,2-dichloroethane to 2-chloroethanol and chloride without use of oxygen or cofactors. The active site is situated in an internal cavity, which is accessible from the solvent, even in the crystal. Crystal structures of the dehalogenase enzyme complexed with iodoacetamide, chloroacetamide, iodide, and chlori...

A regioselective Heck reaction of aliphatic olefins and aryl bromides is realized at internal carbons of olefins. Methanol solvent promoted halide ionization from neutral arylpalladium halide complexes via hydrogen bonding, so as to create cationic aryl-Pd species for regioselective olefin insertion.

Many image processing and simulation tasks are naturally expressed as a pipeline of small computational kernels known as stencils. Halide is a popular domainspecific language and compiler designed to implement stencil algorithms. Halide uses simple language constructs to express what to compute and a separate scheduling co-language for expressing how to perform the computation. This approach ha...