We compared xenodiagnosis with quantitative polymerase chain reaction in skin biopsies from 3 patients with maculopapular or nodular post-kala-azar dermal leishmaniasis (PKDL). All patients infected sand flies. Parasite loads in skin varied from 1428 to 63 058 parasites per microgram. PKDL detection and treatment are important missing components of the kala-azar elimination program.

BACKGROUND Studies performed over the past decade have identified fairly consistent epidemiological patterns of risk factors for visceral leishmaniasis (VL) in the Indian subcontinent. METHODS AND PRINCIPAL FINDINGS To inform the current regional VL elimination effort and identify key gaps in knowledge, we performed a systematic review of the literature, with a special emphasis on data regard...

thirty eight patients with visceral leishmaniasis were reviewed, age ranged from 2 months to 10 years, 74% above 3.5 y, with 24% affection in infants (7 to 12 m), with slight male predilection. all the patients had weight loss, splenomegaly and hepatomegaly, 97% with fever, 92% had positive serology and 63% had positive bone marrow findings. a few patients presented with atypical clinical findi...

in a descriptive analytical study in six villages in meshkin shahr area, the important endemic focus of kala-azar in northwest iran, a kap study was carried out on various aspects of kala-azar in a total of 245 young mothers selected randomly and interviewed the results of the present investigation showed that 93.5% of the mothers were illiterate and only 2.4% of them had acceptable knowledge a...

Mohammad Rahim Ahmadi*, Arsalan Hosseini, Hamid Reza Gheisari, Morteza Yavari Department of Clinical Sciences, Shiraz University, Shiraz, Iran Pathobiology, Shiraz University, Shiraz, Iran Food Hygiene, School of Veterinary Medicine, Shiraz University, Shiraz, Iran Department of Veterinary Medicine, Faculty of Paraveterinary Sciences, Bu-Ali Sina University, Hamedan, Iran Asian Pac J Trop Dis 2...

remain unknown. S. delphini has rarely been identified in horses, but, as we observed, it may be misidentified by conventional methods. Although colonization or contamination appeared most likely in the instances we describe, these findings suggest that this opportunistic pathogen can be found in horses and might be pathogenic in certain situations. Our findings highlight the importance of usin...

Introduction.?About eighteen months ago, we (Napier and Sen, 1940) published a preliminary paper on the treatment of kala-azar by 4 : 4'-diamidino stilbene. At the time our paper was sent to press, there were in the literature? that had arrived in this country?only two detailed reports on cases treated by this drug (Adams and Yorke, 1939; and Adler and Rachmilewitz, 1939). Since then a small sp...

Visceral leishmaniasis or kala-azar is an endemic parasitic disease in some parts of the world which is characterized by fever, splenomegaly, and pancytopenia in most of the cases. Herein we report an 11 month-old male infant with diagnosis of kala-azar who presented with pallor, hepatosplenomegaly, failure to gain weight, and no history of fever. Surprisingly, fever started after beginning of ...