Clinical data identify age as a factor for severe liver fibrosis. We evaluate whether and how aging modulates the fibrotic response in a mouse model. Liver fibrosis was induced by CCl4 injections (thrice weekly for 2 weeks) in 7 weeks- and 15 months-old mice (young and old, respectively). Livers were analyzed for fibrosis, inflammation and remodeling 48 and 96 hours after the last injection. Ol...

Yezihalem Tesfa Dagnaw, Instructor and Assistant Researcher, St. Mary’s University College P.O.Box 16229 Addis Ababa Ethiopia [email protected] Abstract Why we Ethiopians are celebrated for unforgettable images of chronically malnourished children with large skeletal heads clinging to their mothers dried up breasts? Why we are still forced to seek for food aid when there is ample local...

PE/PPE genes, present in cluster with ESAT-6 like genes, are suspected to have a role in antigenic variation and virulence of Mycobacterium tuberculosis. Their roles in immune evasion and immune modulation of host are also well documented. We present evidence that PE32/PPE65 present within the RD8 region are co-operonic, co-transcribed, and co-translated, and play role in modulating host immune...

The issue of measurement invariance is ubiquitous in the behavioral sciences nowadays as more and more studies yield multivariate multigroup data. When measurement invariance cannot be established across groups, this is often due to different loadings on only a few items. Within the multigroup CFA framework, methods have been proposed to trace such non-invariant items, but these methods have so...

This article explores the critical factors and issues that impede the performance of software reliability modeling science. The literature review indicates that software reliability models have not delivered the desirable deliverables that they are intended to realize. The current work suggests that the reasons for such performance incompetence of the software reliability modeling are attribute...

In ongoing discussions participants tend to pick up their smart phones to retrieve relevant information for clarification, severely hampering the flow of the discussion. We introduce ambient search as a variant of information retrieval where a system unobtrusively provides relevant information snippets in the background without the need to steer devices actively. In this demo paper, we describe...

Noroviruses (NoV) in 78 wastewater samples from Luxembourg were quantified, cloned, and sequenced in 2008-2009. The concentrations of NoV genogroup II and the relative occurrences of certain genotypes changed significantly during the winter season. NoV genogroup I was frequently detected by real-time reverse transcription-PCR (RT-PCR), albeit at 30-fold lower concentrations than for genogroup I...

The success of any treatment modality depends on following a precise biological criteria which includes using atraumatic surgical procedures, minimal risk to surrounding tissues, improved visibility, hemostasis and post operative conditions2. Most of the instruments used are either manual or motor driven but in bone surgeries they do not help to achieve the above criteria because they are diffi...

Power control is considered as an important means to combat near-far fading effects and maintain acceptable connections in wireless communications systems. When applying power control in practice, the performance is restricted by a number of fundamental limitations. Here, these are addressed from a control theory perspective. Limited update rate, limited feedback bandwidth, time delays, measure...

In order to capture flexible scenarios, a declarative approach to business process modeling describes constraints that limit a process’ behavior instead of specifying all its allowed enactments. However, current graphical notations for declarative processes are tough to understand, thus hampering a widespread usage of the approach. To overcome this issue, we present a novel notational framework...