نتایج جستجو برای: hbv chronic carriers
تعداد نتایج: 548316 فیلتر نتایج به سال:
Methods Five groups of subjects were enrolled viz. control (n=146), HBV-carriers (n=68), chronic active HBV (n=64), HBV-cirrhotics (n=60) and HBV-related HCC (n=59). Allele-specific-PCR was performed to study various polymorphic forms of IFN-g (+874) and blood levels were estimated by ELISA. Genotype distribution was compared using chi square analysis and the odds ratios (ORs) and 95% CI were c...
BACKGROUND/AIM This study aims to investigate whether the SNPs of CXCR1 gene, could predict the likelihood of viral persistence and/or disease progression. MATERIAL AND METHODS We investigated the association of two different SNPs (rs2234671, and rs142978743) in 598 normal healthy controls and 662 HBV patients from a Saudi ethnic population. The HBV patients were categorized into inactive car...
BACKGROUND Immunomodulators and Nucleotide analogues have been used globally for the dealing of chronic hepatitis B virus (HBV) infection. However, the development of drug resistance is a major limitation to their long-term effectiveness. OBJECTIVES The aim of this study was to characterize the hepatitis B virus reverse transcriptase (RT) protein variations among Iranian chronic HBV carriers ...
Postnatal horizontal transmission of hepatitis B virus (HBV) in early childhood seems to be the predominant method by which high hepatitis B carrier rates in the Middle East are maintained. The prevalence of hepatitis B surface antigen (HBsAg) positive status among siblings of HBV carriers is similar during childhood and adulthood, suggesting that childhood intrafamilial transmission patterns p...
BACKGROUND Immune cells and molecules play a vital role in initiating, maintaining, regulating immunological homeostasis and inflammation in many pathological and physiological processes; however, the changes on expressions and functions of these cells and molecules in hepatitis B virus (HBV) infection have not been elucidated well. OBJECTIVES The current study aimed to determine the expressi...
BACKGROUND AND AIMS The virus/host interplay mediates liver pathology in chronic HBV infection. MiRNAs play a pivotal role in virus/host interactions and are detected in both serum and HBsAg-particles, but studies of their dynamics during chronic infection and antiviral therapy are missing. We studied serum miRNAs during different phases of chronic HBV infection and antiviral treatment. METHO...
In order to evaluate the familial clustering of hepatitis B virus(HBV) and hepatitis C virus(HCV) infections and to elucidate the possible routes of HCV transmission among Korean adults with chronic liver disease, 137 household contacts of 51 chronic carriers of HBsAg and 111 household contacts of 38 controls, and 181 household contacts of 96 anti-HCV positives and 102 household contacts of 76 ...
Recent genome-wide association studies (GWAS) have identified eleven leukocyte telomere length (LTL)-related single nucleotide polymorphisms (SNPs). Since LTL has been associated with risk of many malignancies, LTL-related SNPs may contribute to cancer susceptibility. To test this hypothesis in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC), we genotyped these eleven LTL-related...
OBJECTIVE This study was performed to investigate the correlation between the chronic hepatitis B virus infection and hearing status. This study was performed to investigate the correlation between the chronic hepatitis B virus infection and hearing status. PATIENTS AND METHODS This research was based on 76 hepatitis-B infections as the case group (including 35 HBV carriers and 41 chronic hep...
background hepatitis b virus (hbv) is one of the most common chronic viral infections in the world. iran has a low to intermediate hbv prevalence and approximately 1.5 million people are living with hbv infection. the impact of hbv in iran is unknown and given the very low levels of alcohol consumption, this region provides an opportunity to examine the impact of isolated chronic hbv infection....
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