Background: High-risk behaviors in people with severe mental illnesses, such drug injection by shared equipment and unprotected sex, expose them to the risk of blood-borne infections as hepatitis B virus (HBV) C (HCV) infections. Objectives: This study aimed determine prevalence HBV HCV serum markers illnesses Tehran, Iran. Methods: In this cross-sectional study, schizophrenia, bipolar disorder...

BACKGROUND HBV infection is a major global health problem and ten genotypes (A to J) and multiples subtypes of HBV have been identified, and they show some distinct geographic distributions. The available data on HBV genotype in Iran are very heterogeneous and limited. Therefore in this study, we tried to identify the HBV genotypes by using polymerase chain reaction. METHODS In this cross-sec...

BACKGROUND The association between mutations in the hepatitis B surface antigen (HBsAg) gene and the occurrence of occult HBV (OBI) in patients has not been studied adequately to determine if the two are correlated. The current study was aimed to investigate HBsAg mutations, the genotype of HBV and co-infection with HCV in OBI in the central part of Iran to determine any possible associations. ...

BACKGROUND Hepatitis D virus (HDV) is dependent on hepatitis B virus (HBV) infection. Acute infection with HDV can occur simultaneously with acute HBV infection or be superimposed onto a chronic HBV infection. OBJECTIVES This study aimed to identify cases of HDV and determine its prevalence in patients with chronic HBV infection for the first time study in Isfahan, central Iran. PATIENTS AN...

BACKGROUND The epidemiological impact and the duration of protection provided by infant hepatitis B (HB) vaccination are unknown. OBJECTIVES This study was designed to determine the hepatitis B virus (HBV) infection seromarkers in young adults who have been vaccinated against HBV as the first group of Iranian neonates during 1993 and 1994. PATIENTS AND METHODS We recruited 510 young adults ...

Background: HBV and HCV coinfection is common, particularly in endemic areas and among high risk groups. In this study we have investigated the prevalence of HBV/HCV coinfection and compared the biochemical and serological characteristics of such patients compare with the patients having hepatitis C infection alone. Methods: We studied 207 patients diagnosed as having chronic hepatitis C, with ...

OBJECTIVES Hepatitis B virus (HBV) is a health problem among injection drug users (IDUs) in prison. The aim of this study is to evaluate the association of factors of incarceration with HBV infection in prisoners with history of drug injection in Isfahan, Iran. METHODS In a cross-sectional study, all IDUs inmates were enrolled. Sociodemographic characteristics and associated risk factors were...

Objectives: To assess the prevalence and risk factors for HBV, HCV and HTLV-I co infection in the Iranian HIV positive Injecting Drug Users (IDU) patients admitted in hospital. Methodology: Analyses were based on 154 male IDU patients admitted in Infectious disease ward of Razi Hospital, Ahwaz, Iran, from April 2001 to March 2003. All of them had been tested for HIV infection (Elisa-antibody &W...

BACKGROUND Hepatitis B is the most prevalent chronic infectious liver disease worldwide with serious sequelae. Prevention of the infection can be provided by universal vaccination and improvement in knowledge and behavior about disease transmission. Provision of any educational program requires inquiry about target group baseline knowledge. OBJECTIVES The aim of this study was to assess Irani...

Background: It has been argued that unprecedented degree of human leukocyte antigen (HLA) loci polymorphism within a population is required to avoid the devastating effects of infectious diseases. The present study was conducted to determine the associations between some of HLA class I genes and the outcome of hepatitis B virus (HBV) infection. Methods: Using sequential sampling method, 64 indi...