TongXie-YaoFang (TXYF) can effectively alleviate the symptoms of diarrhea-predominant irritable bowel syndrome (D-IBS) patients. However, the curative mechanism has not been fully clarified. The study was designed to investigate the effect of TXYF on the colonic ion transport induced by serotonin (5-HT) in D-IBS rats. A method of multiple stress (neonatal maternal separation (NMS) combined with...

The Great Plains (Dakota) aquifer system is one of the most extensive in North America, extending from the Arctic Circle to New Mexico, and underlies approximately 94% of Nebraska. In Nebraska, we do not have the physical ground water monitoring data at the scale that is necessary to manage ground water flow systems. However, first-order management strategies for this regional aquifer can be de...

BSC-1 kidney epithelial cells derived from the African green monkey are known to express a Na+HCO3- symport (Jentsch, T. J., Schill, B. S., Schwartz, P., Matthes, H., Keller, S. K., and Wiederholt, M. (1985) J. Biol. Chem. 260, 15554-15560). In the present work, 4,4-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS)-sensitive 22Na+ uptake into confluent monolayers of BSC-1 is measured in the pr...

The mechanism of basolateral membrane base transport was examined in the in vitro microperfused rabbit proximal convoluted tubule (PCT) in the absence and presence of ambient CO2/HCO3- by means of the microfluorometric measurement of cell pH. The buffer capacity of the cells measured using rapid NH3 washout was 42.8 +/- 5.6 mmol.liter-1.pH unit-1 in the absence and 84.6 +/- 7.3 mmol.liter-1.pH ...

Gu, Xiang Q., Hang Yao, and Gabriel G. Haddad. Effect of extracellular HCO3 2 on Na channel characteristics in hippocampal CA1 neurons. J Neurophysiol 84: 2477–2483, 2000. The effect of HCO3 /CO2 on membrane properties of isolated hippocampal CA1 neurons was studied with the use of the whole cell configuration of the patch-clamp technique. Neurons were acutely dissociated from 21to 30-day-old m...

A survey of surface, spring and borehole waters associated with the ophiolite rocks of Cyprus shows five broad water types (1) Mg-HCO3, (2) Na-SO4-Cl-HCO3, (3) Na-Ca-Cl-SO4-OH-CO3, (4) Na-Cl-SO4 and (5) Ca-SO4. The waters represent a progression in chemical reactivity from surface waters that evolve within a groundwater setting due to hydrolysis of the basic/ultrabasic rock as modified by CO2-w...

Abstract Under the present study detailed hydro chemical characterization and human health risk assessment of ground water in Narmada basin was done. The performed based on data collected from 305 groundwater sample stations basin. Hydro evaluation illustrated that cationic ion upper middle dominated by Ca2+ however, lower it Na+ ion. Similarly, anionic HCO3− throughout Chadha plot drawn inferr...

Geothermal resources have been a source of significant clean energy in the world. The Sichuan Province is famous for its abundant geothermal China, especially western Sichuan. Aba area minority region northwestern with resources. In this study, hydrochemical and D-O analyses were conducted on eight collected springs to investigate genetic mechanism resource area. exposed temperatures pH values ...