Background—The first Sibrafiban Versus Aspirin to Yield Maximum Protection From Ischemic Heart Events Post–Acute Coronary Syndromes (SYMPHONY) trial showed no benefit of 2 doses of sibrafiban over aspirin for secondary prevention after acute coronary syndromes. In 2nd SYMPHONY, we compared low-dose sibrafiban plus aspirin (LDS1A), high-dose sibrafiban (HDS), and aspirin alone. Methods and Resul...

3D environment and high cell density play an important role in restoring and supporting the phenotypes of cells represented in cardiac tissues. The aim of this study was therefore to investigate the suitability of high density sphere (HDS) cultures for studies of cardiomyocyte-, endothelial-, and stem-cell biology. Primary adult cardiac cells from nine human biopsies were cultured using differe...

Introduction: Little is known about the prevalence of herbal and dietary supplement (HDS) use among ambulatory patients who use prescription medications or about the risk of adverse drug events (ADEs) related to drug-HDS interactions. Methods: We conducted a secondary analysis of a study of patients who received prescription medications at four primary care practices. We used chart reviews and ...

Sonochemical preparation of Co and Ni promoted MoS(2) supported on alumina was achieved by high-intensity ultrasonic irradiation of isodurene solutions containing molybdenum carbonyl, dicobalt octacarbonyl, elemental sulfur, and Al(2)O(3) or Ni-Al(2)O(3) under Ar flow. The sonochemically prepared catalysts were characterized by elemental analysis, XPS, SEM, TEM, and XEDS, and hydrodesulfurizati...

Using magneto-optical microscopy in combination with ellipsometry measurements, we show that all-optical switching with polarized femtosecond laser pulses in ferrimagnetic GdFeCo is subjected to a threshold fluence absorbed in the magnetic layer, independent of either the excitation wavelength or the polarization of the laser pulse. Furthermore, we present a quantitative explanation of the inte...

The aim of this study was to investigate whether the sperm chromatin structure assay (SCSA) results after swim-up are related to fertilization rates, embryo quality and pregnancy rates following in vitro fertilization (IVF). A total of 223 couples undergoing IVF in our hospital from October 2008 to September 2009 were included in this study. Data on the IVF process and sperm chromatin structure...

Hazardous drugs (HDs) are chemicals that demonstrate one or more of the following characteristics: carcinogenicity, genotoxicity, teratogenicity, reproductive toxicity, or organ toxicity. In addition, newer drugs with a structural or toxicity profile that mimics an agent known to be hazardous by one of the aforementioned criteria also should be treated as such (National Institute for Occupation...

BACKGROUND AND PURPOSE Fall risk assessment is a necessary component of fall prevention programs. Accurate instruments to predict the risk of falling are paramount in identifying the correct patients in need of fall prevention measures. The purpose of this study was to prospectively validate the Hester Davis Scale (HDS) for fall risk assessment in an acute care setting in the South Central Unit...

Herbal and dietary supplement (HDS) use has grown exponentially in the United States. Unfortunately, incidence of HDS-related liver injury proportionally increased. Despite potential for certain HDSs to cause clinically significant injury, they are not regulated by Food Drug Administration. Recent efforts have been made regulate but far removed from scrutiny prescription medications. Scant lite...

Humidifier disinfectant (HD) damage was terrible chemical damage caused by household goods that happened in only South Korea, but still very little is known in HD damage. Up to now, previous research tried to focus on interstitial fibrosis on terminal bronchioles and alveoli because it is a specific finding, compared with other diseases. To figure out whole effects from HDs, much epidemiologic ...