Pressure-volume relntionships and niyocnrdinl oxygen consumption (VOL) were obtiiined in nil isolated heart during ventricular fibrillation, potassium-induced arrest, and isovolumi'tric contractions. The heart was found to be less distensible in fibrillation than in diastole or arrest. The VOL increased from 4.6 to 14.6 ee./.lOO Gm. LV/min. as tlie fibrillatingventricle was distended. Duringarr...

Emergency cardiopulmonary bypass (ECPB) has been investigated experimentally and clinically as an advanced resuscitation method that may rescue patients with refractory cardiac arrest or cardiogenic shock unresponsive to traditional medical interventions. By diverting blood flow from the patient to an extracorporeal heart and lung system capable of providing full cardiac output, ECPB can provid...

TECHNIQUE For patients arriving in cardiopulmonary arrest, emergency department thoracotomy is indicated. For those patients arriving stable enough to be transported to the operating room, median sternotomy is the incision of choice. Penetrating injuries to the heart will inevitably cause bleeding of the myocardium, mandating repair to prevent cardiac tamponade. Suture repair of a cardiac lacer...

TECHNIQUE For patients arriving in cardiopulmonary arrest, emergency department thoracotomy is indicated. For those patients arriving stable enough to be transported to the operating room, median sternotomy is the incision of choice. Penetrating injuries to the heart will inevitably cause bleeding of the myocardium, mandating repair to prevent cardiac tamponade. Suture repair of a cardiac lacer...

BACKGROUND Hospitalized patients with heart failure are at risk for cardiac arrest. The ability to predict who may survive such an event with or without neurological deficit would enhance the information on which patients and providers establish resuscitative preferences. METHODS AND RESULTS We identified 13 063 adult patients with acute heart failure who had cardiac arrest at 457 hospitals p...

Pressure-volume relntionships and niyocnrdinl oxygen consumption (VOL) were obtiiined in nil isolated heart during ventricular fibrillation, potassium-induced arrest, and isovolumi'tric contractions. The heart was found to be less distensible in fibrillation than in diastole or arrest. The VOL increased from 4.6 to 14.6 ee./.lOO Gm. LV/min. as tlie fibrillatingventricle was distended. Duringarr...

Sinus arrest rarely occurs during acute myocardial infarction involving the right coronary artery (RCA) and sinus node (SN) artery. We report a rare case of sinus arrest caused by SN artery occlusion following RCA stenting. A 56-year-old woman with a significant history of RCA stenosis with prior bare metal stenting, presented to the emergency department with anginal chest pain. Initial work up...

The ischemic state of the myocardium of the isolated working rat heart after induction of normothermic ischemic cardiac arrest was assessed by the interrelationship among changes in myocardial ultrastructure, mitochondrial oxidative phosphorylation, and tissue high energy phosphate contents. At all time intervals (10-40 minutes) studied, the ultrastructural changes were more severe in the suben...

Patients with porcelain aorta carry a high risk of cerebral as well as systemic embolism during cardiac surgery. Here we describe a case of severe aortic stenosis and coronary artery disease combined with the circumferentially calcified aorta. The patient was a 77-year-old man who successfully received four coronary artery bypass grafts with in situ arterial grafts without clamping the aorta an...

The mammalian heart has a remarkable regenerative capacity for a short period of time after birth, after which the majority of cardiomyocytes permanently exit cell cycle. We sought to determine the primary postnatal event that results in cardiomyocyte cell-cycle arrest. We hypothesized that transition to the oxygen-rich postnatal environment is the upstream signal that results in cell-cycle arr...