AIMS Several studies have shown the presence of helicobacter species in the human biliary tract and in the intestinal tract of animals. Experimental infection by Helicobacter hepaticus in mice causes chronic hepatitis and hepatocellular carcinoma (HCC). This study investigated whether helicobacter species could be detected in the liver of patients with HCC. METHODS Liver samples from 20 patie...

HELICOBACTER PYLORI IN SLEEVE GASTRECTOMIES: Prevalence & Rate of Complications. Prevalence of Helicobacter pylori has not been established in sleeve gastrectomy specimens and yet initial observations indicate that it is significant. The aim is to determine prevalence of Helicobacter pylori and correlate with rate of post-operative complications. A total of 89 Sleeve gastrectomies were identifi...

UNLABELLED Gastric cancer with the annual mortality of 700 000 is the second cause of death in the world. Iran with the annual incidence of 37 in 100 000 is among areas with high risk of gastric cancer. In Iran, Khuzestan Province with the annual incidence of 10 -15 in 100 000 is among areas with moderate risk. The role of Helicobacter pylori infection in distal gastric cancer as one of the mos...

The discovery of the spiral bacterium Helicobacter pylori and its causative role in gastric disease in humans has brought a dramatic change to gastroenterology. Although spiral bacteria have been known for more than a century to infect the stomachs of dogs and cats, recent research has been conducted mainly in the wake of interest in H. pylori. H. pylori has not been found in dogs and only very...

Molecular and genetic studies have demonstrated that members of the Toll-like receptor (TLR) family are critical innate immune receptors. TLRs are recognition receptors for a diverse group of microbial ligands including bacteria, fungi, and viruses. This study demonstrates that distinct TLRs are responsible for the recognition of Helicobacter lipopolysaccharide (LPS) versus intact Helicobacter ...

Helicobacter pylori and latent toxoplasmosis are widespread diseases that have been associated with cognitive deficits and Alzheimer's disease. We sought to determine whether interactions between Helicobacter pylori and latent toxoplasmosis, age, race-ethnicity, educational attainment, economic status, and general health predict cognitive function in young and middle-aged adults. To do so, we u...

Helicobacter pylori infection is one of the most frequent causes of dyspepsia in the general population. As gastrointestinal symptoms are a common complaint among HIV-positive persons, the purpose of the present study is to assess the role of Helicobacter pylori infection in this category of patients. We performed a retrospective, case-control study on two groups of HIV-infected patients admitt...

BACKGROUND Gastrointestinal infections with pathogenic Helicobacter species are commonly treated with combination therapies, which often include amoxicillin. Although this treatment is effective for eradication of Helicobacter pylori, the few existing reports are less clear about antibiotic susceptibility of other Helicobacter species. In this study we have determined the susceptibility of gast...

BACKGROUND Changes in bacterial populations termed "dysbiosis" are thought central to ulcerative colitis (UC) pathogenesis. In particular, the possibility that novel Helicobacter organisms play a role in human UC has been debated but not comprehensively investigated. The aim of this study was to develop a molecular approach to investigate the presence of Helicobacter organisms in adults with an...

Helicobacter pyloriinfection remains the leading cause of a number gastroduodenal diseases. Although various eradication regimens are used to reduce associated morbidity and mortality, prevalence this bacterial infection is still disproportionately high worldwide, mainly due antibiotic resistance. In these conditions, it very important strictly follow basic recommendations for choosing an thera...