The effects of temperature and salinity stress on hemato-immunological factors in juvenile Labeo rohita fed normal or elevated levels of tryptophan were studied. Fish were fed diets with 0.35% (control), 0.7%, or 1.4% tryptophan for 60 days, then exposed to temperature and/or salinity stress for the next 30 days with the same feeding regime. The specific growth rate (SGR) was significantly redu...

Cancer is a leading cause of death in children. In the past decades, there has been a marked increase in overall survival of children with cancer. However, children whose treatment includes hematopoietic stem cell transplantation still represent a subpopulation with a higher risk of mortality. These improvements in mortality are accompanied by an increase in complications, such as respiratory a...

Stable ferro-forms of hemoglobins containing various hemes such as dimethyl proto-, dhnethyl meso-, etio-, meso-, hemato-, and deuteroheme were prepared by combination of human globin with hemes, followed by reduction with dithionite and purification with carboxymethyl Sephadex column. Sedimentation coefficients of these hemoglobins were ah near to 4.0 S and chemical analysis showed that 4 mole...

Here we report that a new nonobese diabetic/severe combined immunodeficient (NOD/SCID) mouse line harboring a complete null mutation of the common cytokine receptor chain (NOD/SCID/interleukin 2 receptor [IL2r] null) efficiently supports development of functional human hemato-lymphopoiesis. Purified human (h) CD34 or hCD34 hCD38 cord blood (CB) cells were transplanted into NOD/SCID/IL2r null ne...

BACKGROUND Early mesoderm can be classified into Flk-1+ or PDGF receptor alpha (PDGFRα)+ population, grossly representing lateral and paraxial mesoderm, respectively. It has been demonstrated that all endothelial (EC) and hematopoietic (HPC) cells are derived from Flk-1+ cells. Although PDGFRα+ cells give rise to ECs/HPCs in in vitro ES differentiation, whether PDGFRα+ population can become hem...

Stable ferro-forms of hemoglobins containing various hemes such as dimethyl proto-, dhnethyl meso-, etio-, meso-, hemato-, and deuteroheme were prepared by combination of human globin with hemes, followed by reduction with dithionite and purification with carboxymethyl Sephadex column. Sedimentation coefficients of these hemoglobins were ah near to 4.0 S and chemical analysis showed that 4 mole...