A reversed-phase liquid chromatographic method combined with fluorescence and multiple mass spectrometric detection in series is presented for the separation and structure elucidation of bisphenol A diglycidyl ether (BADGE) and novolac glycidyl ether (NOGE) derivatives. Atmospheric pressure chemical ionization in the positive ion mode and collision induced fragmentation in the ion trap allowed ...

A method is presented for the resolution of urinary 17-ketosteroids (17-KS) by gasliquid chromatography (GLC) for clinical application. Hot acid hydrolysis with sulfuric acid is followed by ether extraction, 1 N NaOH wash, and NaOH pellets to serve for both purifying and drying agent. All steps take place in the same re3ction tube and are adapted for mechanical shaking. The method allows one an...

We describe a method for obtaining profiles of neutral and acidic substances present in human cerebrospinal fluid (CSF) by gas-liquid chromatography. Metabolites extracted with ethyl acetate and ether are converted to methyl ester, trimethylsilyl ether derivatives. With this technique, acidic metabolites of brain amines, and neutral metabolites of dopamine and norepinephrine have been identifie...

Methyl and ethyl thioether groups were introduced at all primary positions of α-, β-, and γ-cyclodextrin by nucleophilic displacement reactions starting from the corresponding per-(6-deoxy-6-bromo)cyclodextrins. Further modification of all 2-OH positions by etherification with iodo terminated triethylene glycol monomethyl ether (and tetraethylene glycol monomethyl ether, respectively) furnished...

(I) The alkenyl ether derivatives of phospholipids (plasmalogens) react at slower rates than the acyl analogs in several enzyme-catalyzed reactions. (2) Alkenylglycerol-3-phosphorylcholine is essentially inert as a substrate for acyl-CoA : phospholipid acyltransferase. This result suggests that in viuo the a-acyl substituent may be present before the alkenyl ether group is formed in the molecul...