Anaphyactoid purpura or HenochSchonlein purpura, a common vasculitis in children, is characterized by non-thrombocytopenic purpura, arthritis or arthralgia, abdominal pain, gastrointestinal hemorrhage and nephritis. The immunopathology of these lesions is that of leukocytoclastic vasculitis characterized by deposition of immunoglobulin A and complement 3, but is often accompanied by IgG, IgM, f...

Henoch-Schonlein purpura (HSP) is an immune-mediated vasculitis. HSP presents with purple spots on the skin (purpura), arthralgia, digestive problems, and kidney injury. HSP is most commonly seen in children, and rarely presents in adults. The pathogenesis involves the deposition of immune complexes in small to medium size blood vessels which leads to necrosis and inflammation. Most patients re...

A case of Henoch-Schönlein purpura with fatal pulmonary haemorrhage and capillaritis is described.

OBJECTIVE To determine the clinical profile of children with Henoch-Schonlein purpura (HSP). DESIGN Hospital based descriptive follow-up study. SUBJECTS 45 patients attending the Pediatric Rheumatology and Immunology clinic over the last 4 years. RESULTS The patients were aged between 2.5-12 years with a male to female ratio of 2:1. All cases had palpable purpura. Gastrointestinal involve...

non-ipregnant cervix in vitro have a tendency to contract in response to PGF2,, and to relax with PGE2.9 It is therefore possible that PGE2 is less likely to cause or allow such damage to occur, though it must be said that these experiments have not been performed using strips of pregnancy cervix in vitro, nor have such observations been made in vivo. That cervicovaginal fistulae have also been...