Although most hepatitis E virus (HEV) infections are asymptomatic, some can be severe, causing fulminant hepatitis and extra-hepatic manifestations, including neurological and kidney injuries. Chronic HEV infections may also occur in immunocompromised patients. This review describes how our understanding of the pathogenesis of HEV infection has progressed in recent years.

Hepatitis E virus (HEV) infection is an emerging health concern in developing and developed countries, such as Japan. Five cases have recently been diagnosed as hepatitis E. Of interest, 3 of them had rheumatoid arthritis (RA), although a previous study demonstrated a lack of association between HEV and RA. One of the other patients developed autoimmune hepatitis and was successfully treated wi...

Cleaning and Disinfection • Little is known about virus survival outside the host; however, HEV is thought to be somewhat stable in the environment since feces are an important source of infection. • Heating pork products to an internal temperature of 71°C (160°F) for 20 minutes is required to completely inactivate HEV. • HEV is potentially susceptible to disinfection with acids like acetic aci...

In October 2007, an epidemic of hepatitis E was suspected in Kitgum District of northern Uganda where no previous epidemics had been documented. This outbreak has progressed to become one of the largest hepatitis E outbreaks in the world. By June 2009, the epidemic had caused illness in >10,196 persons and 160 deaths.

CASE PRESENTATION A 63-year-old Indian man presented to the emergency department with fever, nausea, chills, and generalized abdominal pain that had been present for 2 weeks. Th e patient had been in India for the past 3 months and began to feel ill during the last week of his visit. He was seen by a local physician and was found to have abnormal liver function tests and was treated with sparfl...

Acute pancreatitis is considered to be an extremely rare extrahepatic manifestation of acute viral hepatitis E. The incidence is reported to be around 5%-6% in the available case series. It has usually been reported in non-fulminant cases of acute viral hepatitis E in the second or third week of illness, with a favourable outcome. Here, we report the case of a young male subject with acute vira...

A strain of hepatitis E virus (SAR-55) implicated in an epidemic of enterically transmitted non-A, non-B hepatitis, now called hepatitis E, was characterized extensively. Six cynomolgus monkeys (Macaca fascicularis) were infected with a strain of hepatitis E virus from Pakistan. Reverse transcription-polymerase chain reaction was used to determine the pattern of virus shedding in feces, bile, a...

The liver is an organ that withstands a lot of insults due to various things such as infection, toxins and even our own immune system. There are injuries the relatively common in medicine viral hepatitis caused by different strains Hepatitis A-E, autoimmune hepatitis, injury drugs acetaminophen. However, syphilis causing not seen often there certain features distinguish syphilitic should be rep...

The western region of the Brazilian Amazon Basin has long been shown to be a highly endemic area for hepatitis B and hepatitis D viruses. Data concerning the prevalence of hepatitis C and E viruses in this region are still scarce. In this study we investigated the presence of hepatitis A, B, C, D and E viruses infection in communities that live along the Purus and Acre rivers in the states of A...