The curative effects of Chinese herbal compounds result from the coordination of numerous natural compounds. We aimed to review the mechanism of action of Traditional Chinese Medicine (TCM) compounds (TCMC), explore the rationality of formulation theory and synergistic effects in TCM compounds, and analyze the effectiveness of drug compatibility of TCMC in molecular biology. This literature rev...

BACKGROUND Because dietary supplements are not subject to the same regulations that pharmaceuticals are, there is concern among medical professionals that these products may lack purity or potency. OBJECTIVE To determine the variability in a range of ginseng herbal products available in the United States, we identified and measured the concentration of marker compounds by using HPLC and liqui...

Herbal medicines include a range of pharmacologically active compounds: in some cases it is not well understood which ingredients are important for a therapeutic effect. The supporters of herbal medicine believe that isolated ingredients in the majority of cases have weaker clinical effects than whole plant extract, a claim that would obviously require proof in each case. Generalizations about ...

Diesun Miaofang (DSMF) is a traditional herbal formula, which has been reported to activate blood, remove stasis, promote qi circulation and relieve pain. DSMF holds a great promise for the treatment of traumatic injury in an integrative and holistic manner. However, its underlying mechanisms remain to be elucidated. In the present study, a systems pharmacology model, which integrated cluster l...

Heat stress negatively affects the productivity of chickens in commercial poultry farms in humid tropics. In this study, the concentrations and types of the antioxidant compounds of eight Chinese herbal medicines, which have previously demonstrated promising effects on suppressing heat stress as a mixture, were investigated using reversed-phase High Performance Liquid Chromatography, spectropho...

Liu Zhang 1, Fengxi Li 1, Chunyu Wang 2, Lu Zheng 1, Zhi Wang 1, Rui Zhao 3,* and Lei Wang 1,* 1 Key Laboratory of Molecular Enzymology and Engineering of Ministry of Education, School of Life Sciences, Jilin University, 2699 Qianjin Street, Changchun 130000, China; [email protected] (L.Z.); [email protected] (F.L.); [email protected] (L.Z.); [email protected] (Z.W.) 2 State Key Laborar...

The rhizome of ginger is used widely both as a seasoning and herbal medicine. The active compounds contained in ginger are divided into two groups: volatile essential oils and fragrant or harsh phenol compounds. Two types of gingers, fresh and dried, are used in the herbal medicine. There exist differences in the chemical composition between fresh and dried gingers that might result in differen...

OBJECTIVE To screen antitumor active compounds, drug-like or leading compounds from Chinese traditional and herbal drugs. METHODS Eleven coumarin compounds isolated from the Chinese traditional and herbal drugs were studied for their antitumor activities in vitro by determining the inhibition rates against growth of human bladder carcinoma cell line E-J. RESULTS It showed that umbelliferone...

Phytogenic agents have traditionally been used by herbalists and indigenous healers for the prevention and treatment of peptic ulcer. This article reviews the anti-acid/anti-peptic, gastro-protective and/or anti-ulcer properties of the most commonly employed herbal medicines and their identified active constituents. Botanical compounds with anti-ulcer activity include flavonoids (i.e. quercetin...

Artemisia capillaries Thunb, Gardenia jasminoides Ellis, and Rheum officinale Baill have been combined to treat jaundice for thousands of years. Studies have revealed that these herbs induce anti-hepatic fibrosis and anti-hepatic apoptosis and alleviate hepatic oxidative stress. This study aims to determine the quality and quantity of an herbal formulation (Chinese name: Yin-Chen-Hao-Tang) usin...