The aim of this study is to systematically review the literature with regards to surgical treatment of patients with hip joint osteochondromas, and to report our surgical management of three paediatric patients who had femoral neck or acetabular osteochondromas in association with acetabular dysplasia. We performed a systematic review using PubMed and Embase databases for all studies that repor...

Our colleague, L. G. Parsons', has briefly outlined the historical facts regarding a disorder of the skeleton bearing the various names-hereditary deforming chondrodystrophy, multiple cartilaginous exostosis, diaphysial aclasis (Keith) or Ollier's disease; and Brailsford' has recorded the radiological details of a similar condition under the term chondro-osteodystrophy. The disease produces a s...

A 14-year-old boy was admitted to our hospital due to persisting pleuritic pain in the right lower hemithorax, which presented after athletic activities. Chest X-ray showed a right hemothorax for which a chest tube was inserted. The patient’s medical history was positive for exostoses of both humeri and the left femur, for which he had undergone an operation at the age of 5 and 8 years, respect...

BACKGROUND This study aimed to report the radiographic presentation of involved hips in children with hereditary multiple exostoses (HME). This included radiographic hip measurements, osteochondromas location, and relationship with hip subluxation. METHODS Anteroposterior pelvis radiographs of children with HME, seen between 2003 and 2014, were retrospectively reviewed. Only patients who were...

Hereditary multiple exostoses (HME) is an inherited autosomal dominant disorder characterised by the presence of multiple exostoses, in fact benign cartilaginous tumors (enchondromata on the long bones). A six-year-old boy was found to have multiple osteochondromas on the legs, arms and ribs. Unusually, one of the osteochondromas on the right arm was huge (5 x 6 cm) and painful. X ray confirmed...

Hereditary multiple exostoses (HME) is a genetically heterogeneous human disease characterized by the development of bony outgrowths near the ends of long bones. HME results from mutations in EXT1 and EXT2, genes that encode glycosyltransferases that synthesize heparan sulfate chains. To study the relationship of the disease to mutations in these genes, we generated Ext2-null mice by gene targe...

We present a 22-year-old man with osteochondromatosis and osteochondroma involving bilateral patella and patellar tendon with restriction of joint movement and severe arthritis.