Despite great advances in solid organ transplantation (SOT) in recent decades, infection remains a major cause of morbidity and mortality among SOT recipients. Members of the herpesvirus family are the most common viral pathogens causing disease in this patient population. Herpes viruses are large enveloped DNA viruses that commonly reactivate during periods of severe immunosuppression. Current...

Thermal destruction rate curves were determined for adenovirus 12, reovirus 1, and herpes simplex virus in sterile milk, raw milk, raw chocolate milk, and raw ice cream mix. At 40 to 60 C, the curves were asymptotic to the base line. At 65 C, which is near the pasteurization standard, the curves approached a first-order reaction. Thermal resistance studies, by means of in vivo assays, of Molone...

Background: Herpes simplex virus (HSV) encephalitis is the most common cause of sporadic encephalitis, with significant morbidity and mortality that are effectively reduced by antiviral treatment. Herpes simplex infection in pregnant women rarely results in encephalitis. The most common symptoms of a pregnant woman with herpes simplex infection are colds and skin vesicles. Herpetic encephalitis...

Future cancer therapies will be molecular cures. They will correct, block or destroy cancer cells by targeting molecular changes that lead to carcinogenesis. Destroying cancer cells can be done using oncolytic viruses. By blocking antibody mediated neutralization of oncolytic viruses, Herpes simplex virus type 1 glycoproteins E and I could be used in the adjuvant treatment of cancer for improvi...

Rabbit eyes experimentally infected with either type 1 or type 2 herpes simplex viruses occasionally released virus spontaneously. Injection of adrenalin was not highly effective for stimulating virus release but did seem to have a slight and erratic activating capacity. No spontaneous virus release were detected from the eyes of six cats infected with cat herpesvirus, but, when adrenalin was a...

Presently marketed vaginal barrier agents are cytotoxic and damage the vaginal epithelium and natural vaginal flora with frequent use. Novel noncytotoxic agents are needed to protect women from sexually transmitted diseases. One candidate compound is a high-molecular-mass form of soluble poly(sodium 4-styrene sulfonate) (T-PSS). The antimicrobial activity of T-PSS was evaluated in primary cultu...

background and objectives: meningoencephalitis in iranian children is frequent, but encephalitis is rare .the frequency of hhv-6 and hhv-7 in central nervous system diseases of our children is unclear. the aim of this study was searching the dna-s of hhv-6 & hhv-7 in csf samples of children with meningoencephalitis  materials and methods: a cross sectional study (2007-2009) was done in ped...

Currently HIV infection in Kazakhstan is mainly spread among population groups with risk taking behavior (injection drug users - IDUs, sex workers SWs). The lesions and fatalities patients are caused by complications, i.e. the development of opportunistic infections secondary diseases. Timely diagnosis these conditions determines success treatment life expectancy patients. Among superinfections...