Nonomuraea gerenzanensis ATCC 39727 produces the glycopeptide antibiotic A40926, which is natural precursor of semi-synthetic, last-resort drug dalbavancin. To reduce cost dalbavancin production, it mandatory to improve productivity producing strain. Here, we report that exposure N. wild-type population sub-inhibitory concentrations A40926 led isolation differently resistant phenotypes a divers...