Two recent studies, from France (Nataf et al., 2006) and the United States (Geier & Geier, 2007), identified atypical urinary porphyrin profiles in children with an autism spectrum disorder (ASD). These profiles serve as an indirect measure of environmental toxicity generally, and mercury (Hg) toxicity specifically, with the latter being a variable proposed as a causal mechanism of ASD (Bernard...

Heavy metals, like many other chemical elements, are naturally present in the environment; however, concentrations of these metals various environmental matrices have increased through their intensive use human activities (such as industry, mining and agriculture). Among heavy cadmium (Cd) mercury (Hg) induce a wide variety defects animals. While effects been widely documented, single exposure ...

Nonlethal indices of contaminant exposure can facilitate research on the accumulation and effects of contaminants in wildlife. Here, we tested the efficacy of using amputated toes ("toe clips"), a common byproduct when marking amphibians in population and genetic studies, to determine mercury (Hg) concentrations in amphibians. We examined total mercury (THg) concentrations in American toads (Bu...

In this study we investigated the additive effect of mercury on the brain mitochondrial dysfunction in experimental autoimmune encephalomyelitis (EAE) model. Experimental animals (female C57BL/6 mice) are divided into four groups (n = 8); control, Hg, EAE, EAE with Hg. EAE model of MS induced by injecting myelin oligodendrocyte glycoprotein (MOG). Neurobehavioral alterations are recorded and th...

Urban and rural areas may have different levels of environmental contamination and different potential sources of exposure. Many metals, i.e., arsenic (As), lead (Pb), and mercury (Hg), have well-documented negative neurological effects, and the developing fetus and young children are particularly at risk. Using a database of mother and child pairs, three areas were identified: a rural area wit...

Many studies have found that mercury (Hg) exposure is associated with selenium (Se) accumulation in vivo. However, human studies are limited. To study the interaction between Se and Hg, we investigated the total Se and Hg concentrations in body fluids and serum Se-containing proteins in individuals exposed to high concentrations of Hg. Our objective was to elucidate the possible roles of serum ...

Abstract Heavy metal ion pollution is always a serious problem worldwide. Therefore, monitoring heavy ions in environmental water crucial and difficult step to ensure the safety of people environment. A mercury (Hg 2+ ) fluorescence probe with excellent sensitivity selectivity described here. The functionalized graphitic carbon nitride nanosheets (T/G-C 3 N 4 was fabricated using melamine as pr...

AIMS Exposure to high glucose (HG) stimulates reactive oxygen species (ROS) production by NADPH oxidase in cardiomyocytes, but the underlying mechanism remains elusive. In this study, we have dissected the link between glucose transport and metabolism and NADPH oxidase activation under hyperglycaemic conditions. METHODS AND RESULTS Primary cultures of adult rat cardiomyocytes were exposed to ...

Atmospheric mercury (Hg) temporal and spatial patterns must be measured accurately in order to adequately understand the role of this pathway as it relates to Hg toxicity and exposure of humans and wildlife to Hg. It is also important to understand the distribution of the different chemical forms (elemental, oxidized, or particle bound) and specific compounds in air (e.g., HgCl2, HgBr2, HgO, Hg...

BACKGROUND AND PURPOSE Hemorrhage is known to occur in posterior reversible encephalopathy syndrome (PRES), but the characteristics have not been analyzed in detail. The purpose of this study was to evaluate the imaging and clinical features of hemorrhage in PRES. MATERIALS AND METHODS Retrospective assessment of 151 patients with PRES was performed, and 23 patients were identified who had in...