OBJECTIVES This study sought to assess changes in troponin levels, underlying conditions, and the prognostic implications in elderly subjects from the community. BACKGROUND Cardiac troponin levels are often detectable in community dwellers when sensitive assays are applied. However, information on the course of troponin levels over time is limited. METHODS Cardiac troponin I (cTnI) was meas...

Background Data relating high-sensitive troponin T (hs-cTnT) to long-term myocardial function and damage in patients after STEMI are lacking. We evaluated the use of serial and peak concentrations of hs-cTnT versus creatine kinase (CK), lactate dehydrogenase (LDH) and high sensitive C-reactive protein (hs-CRP) for prediction of myocardial function as well as infarct scar assessed by cardiac mag...

BACKGROUND Although complex scores were recommended for diagnosis of pulmonary embolism (PE), acceptance in clinical practice is limited. In our Emergency Department a symptom-based algorithm for patients with suspected PE including computed tomographic pulmonary angiography (CTPA) and D-dimer testing was implemented. PATIENTS AND METHODS The cases of 492 patients presenting with either chest...

Troponin B is an inhibitor of the Mg(++)-activated ATPase activity of actomyosin. The inhibitory effect, which is observed, however, depends upon whether tropomyosin is also present. In the absence of tropomyosin the inhibition by troponin B is markedly reduced by increasing the ionic strength from 0.03 to 0.07, but is not affected by calcium up to a concentration of 10(-4)M. Troponin A relieve...

Rapid identification and treatment of patients with a myocardial infarction (MI) is mandatory. We studied the diagnostic capacities of a sensitive troponin assay for detection of MI in emergency department patients within 2 hours after arrival. The study included 157 patients suspected of having non-ST-elevation acute coronary syndrome. Blood was drawn on arrival (T0) and 2 (T2), 6, and 12 hour...

Objective: This study aimed to investigate if the Homocysteine has recently been proposed as a serious predictive biomarker for Covid-19 infection severity. Method: In this case-control study, which involved 90 participants, 5 ml of venous blood specimen was reserved each participant, measure homocysteine, troponin-I, and high sensitive C-reactive protein in their blood, find there an associati...

Background and Objectives:  The aim of this study was to survey the relationship between the level of  creatinine,cardiac troponins serum and the function of  the left ventricle in patients with  kidney insufficiency,without acute coronary syndrome. Materialsand Methods:The sample  was150 patients with nondialysis chronic kidney disease without  acute  coronary  syndrome,  hospitalized  at  I...

OBJECTIVE We sought to determine the effect of patient selection on the 99th reference percentile of 2 sensitive and 1 high-sensitivity (hs) cardiac troponin assays in a well-defined reference population. METHODS Individuals>45 years old were randomly selected from 7 representative local community practices. Detailed information regarding the participants was collected via questionnaires. The...