نتایج جستجو برای: hilbert ov
تعداد نتایج: 31637 فیلتر نتایج به سال:
Background: Insulin resistance (IR) is frequently associated with hepatitis C virus (HCV) infection, and development of IR can occur early in the course of HCV infection and promote hepatic fibrosis. Aim of the Study: We aimed to assess the impact of IR on the development of oesophageal varices (OV) in HCV-related liver cirrhosis. Subjects and Methods: We enrolled 80 HCV-related liver cirrhosis...
Glyoxal, methylglyoxal and other physiological alpha-oxoaldehydes are formed by the lipid peroxidation, glycation and degradation of glycolytic intermediates. They are detoxified enzymically by the glyoxalase system. To investigate the physiological function of glyoxalase I in parasitic organisms, the cDNA for glyoxalase I from the filarial nematode Onchocerca volvulus (designated Ov-GloI) has ...
The expression of appropriate ensembles of ionic channels is necessary for the differentiation and normal function of vertebrate neurons. Cell-cell interactions may regulate the expression and properties of ionic channels in embryonic neurons. Previous studies have shown that the expression of A-type K+ channels (IA) and Ca2+-activated K+ channels (lK[Ca]) is abnormal in chick ciliary ganglion ...
Oncolytic viruses (OV) were first observed in early clinical studies in patients with malignancies where tumour regressions were observed to coincide with viral infections or with live virus vaccinations. Since these early reports, studies using OV have progressed from anecdotal and controlled infections to specifically selecting or genetically modifying viruses for cancer treatment. OV are int...
A recently reported chitinase gene, expressed in the infective, third-stage (L3) larvae of the human filarial parasite Onchocerca volvulus, belongs to the family 18 glycosyl hydrolases and has been designated Ov-chi-1. The gene product of Ov-chi-1 is chitinolytic. Allosamidin ablates activity of the native enzyme in a dose-dependent manner but did not significantly inhibit the moulting of L3 la...
Functional Near Infrared Spectroscopy (fNIRS) can non-invasively capture dynamic cognitive activation and underlying physiological processes by measuring changes in oxy- and deoxy-hemoglobin levels, correlated to brain activation. It is a portable, inexpensive and user-friendly device which is easily adapted to the outpatient setting for the assessment of cognitive functions after Traumatic Bra...
The aim of this study was to evaluate the oxidative stress in ovaries and corpus luteum (CL) Bos taurus indicus females oxidant effect CL ovarian tissues regions near, intermediate, or distant from it. Ovaries (n=12) Nelore heifers (n=6) were collected a slaughterhouse fragmented. Experiment 1, each ovary obtained three fragments, resulting 18 fragments with (OV+CL) another without (OV-CL). Thr...
The chemoreception role of moth ovipositor has long been suggested, but its molecular mechanism is mostly unknown. By transcriptomic analysis of the female ovipositor-pheromone glands (OV-PG) of Chilo suppressalis, we obtained 31 putative chemoreception genes (9 OBPs, 10 CSPs, 2 ORs, 1 SNMP, 8 CXEs and 1 AOX), in addition to 32 genes related to sex pheromone biosynthesis (1 FAS, 6 Dess, 10 FARs...
The use of engineered viral strains such as gene therapy vectors and oncolytic viruses (OV) to selectively destroy cancer cells is poised to make a major impact in the clinic and revolutionize cancer therapy. In particular, several studies have shown that OV therapy is safe and well tolerated in humans and can infect a broad range of cancers. Yet in clinical studies OV therapy has highly variab...
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