In a prospective evaluation of percutaneous Trucut needle biopsy for localised intrathoracic lesions in 89 patients histological specimens were obtained in 81. Malignancy was diagnosed in 66 cases. Subsequently definitive histological reports were available in 18 of these patients with complete concordance of malignant cell type. Sixteen patients had non-malignant histological appearances, whic...

A method of double labeling a set of serial histological sections was performed to produce multiple three-dimensional (3D) reconstructions from the same segment of injured spinal cord. Alternate groups of consecutive histological sections were stained with Luxol fast blue with cresyl violet and Mallory's trichrome in order to reconstruct two different 3D images that reveal different pathologica...

Technical innovations in brain tumour diagnostic and therapy have led to significant improvements of patient outcome and recurrence free interval. The use of technical devices such as surgical microscopes as well as neuronavigational systems have helped localising tumours as much as fluorescent agents, such as 5-aminolaevulinic acid, have helped visualizing pathologically altered tissue. Noneth...

The problem that we investigate in the present paper is the improvement of the analysis of the primary tumor mass, in patients with advanced neuroblastoma, using X-ray computed tomography (CT) exams. To achieve this goal, we propose a methodology for the estimation of the histological content of the mass that comprises a technique for semi-automatic segmentation of the primary tumor mass in CT ...

Ultrasound imaging is a non-invasive technique to assess organ function. Its potential application in rodents evaluate respiratory function remains poorly investigated. We aimed and validate ultrasound rats analyze inspiratory expiratory muscles. measured parameters provide normal eupneic values. Histological studies plethysmography were used the physiological implications. A linear relationshi...