Inspection of the biopsy samples microscopically plays a vital role in the definitive diagnosis of cancer. To overcome the subjectivity in pathologists’ decision, objective analysis of the stomach biopsy samples is carried out in this work. At the tissue level, malignancy leads to distortions in glandular structure and nearby supporting tissue namely, stroma. These pathological alterations are ...

background: wound infection has become a major medical problem in recent years. this is usually caused by gram-positive bacteria, especially staphylococcus aureus. since antimicrobial resistance to current drugs has critically been developed in these causative microorganisms, substitution medicine has become one of the main interests within  researchers. objectives: the aim of this study was to...

Much progress has been made since the conceptualization of tumor angiogenesis-the induction of growth of new blood vessels by tumor-as a salient feature of clinically significant primary or metastatic cancers. From a practicing histopathologist's point of view, we appraise the application of this concept in breast cancer with particular reference to the evaluation of proangiogenic factors and t...

The occurrence and significance of HHV-6 and HHV-7 were investigated in pulmonary tissue from lung transplant recipients. Eighty-seven transbronchial biopsies from 30 patients were studied by quantitative real-time PCR; the association with histopathological features was investigated. HHV-6 and HHV-7-DNA were detected in 6.9% and 9.2% transbronchial biopsies, respectively. A significant associa...

The ameloblastoma, because of its aggressive clinical behavior and its histological feature apparently benign, constitutes a puzzling paradox. Some hypotheses concerning this strange clinicalhistologic contradiction are analyzed, as well as the additional paradox represented by the neoplastic parenchyma itself, in which a tissue consisting of cells nominally able to form enamel do not elaborate...

Acute appendicitis is one of the most common surgical conditions that affect about seven percent of the population. The histopathologic stages of appendicitis are important to regarding prognosis. To evaluate pathologic features of appendix after operation, this study was designed. 2753 appendices specimen that had been received to department of pathology of two major hospitals in Kerman-Iran d...

PURPOSE To evaluate the classification of punctal stenosis based on the shape of the external punctum, clinical characteristics and histopathologic features. METHODS Patients who experienced tearing and were diagnosed with punctal stenosis were evaluated in this study. Punctal stenosis was classified according to the shape of the lower external punctum, which included membranous type, slit ty...

OBJECTIVE To determine whether collagen induced arthritis (CIA) in mice can be satisfactorily induced by a single immunisation and whether this model has some advantages compared with conventional CIA, which is induced by two immunisations. METHODS The incidence of arthritis was observed under different immunisation conditions (variation of species of Mycobacterium included in complete Freund...

labeo rohita fingerlings were reared in freshwater and exposed to different concentrations of lead nitrate. after the exposure, one fish was sacrificed from each dose and the gill arches were removed. the ultrastructural changes on the gills of this cyprinid fish were investigated through scanning electron microscope (sem). lead treated gill tissues showed certain marked changes such as uplifti...