OBJECTIVES Marine organisms are known as a potential source of natural products, which contain bioactive substances with therapeutic properties. Sea cucumbers are prominent among marine organisms because of their dietary and therapeutic applications. In addition, they have capacity of synthesizing saponins molecules and other metabolites with therapeutic properties such as antitumor, antimicrob...

To study the new antifungal active triterpene glycosides of sea cucumber Holothuria scabra. Triterpene glycosides from Holothuria scabra were separated and purified by silica gel chromatography, reversed-phase silica gel chromatography and RP-HPLC. Their structures were elucidated on the basis of spectral data and chemical evidence. Three triterpene glycosides were identified as scabraside A (1...

This paper reports on some sea cucumbers (Holothuroidea) in the collections of the NHMUK, taken off the coast of Ghana. Most result from collections around Accra during the years 1949-52. A couple of other species are included. Altogether six species are here reported, viz. Holothuria (Holothuria) dakarensis Panning, 1939; Holothuria (Semperothuria) imitans Ludwig, 1875; Holothuria (Vaneyothuri...

The dermis of sea cucumbers is a catch connective tissue or mutable connective tissue that exhibits large changes in mechanical properties. A stiffening protein, tensilin, has been isolated from the sea cucumber Cucumaria frondosa. We purified a similar protein, H-tensilin, from Holothuria leucospilota, which belongs to a different family to C. frondosa. H-tensilin appeared as a single band wit...