نتایج جستجو برای: hookworm

تعداد نتایج: 1659  

2016
Jon J. Vermeire Brian M. Suzuki Conor R. Caffrey

Hookworm infection is chief among soil-transmitted helminthiases (STHs) for the chronic morbidly inflicted. Deworming via mass drug administration (MDA) programs most often employs single doses of benzimidazole drugs to which resistance is a constant threat. To discover new drugs, we employ a hamster model of hookworm infection with Ancylostoma ceylanicum and use albendazole (ABZ; 10 mg/kg oral...

Journal: :WHO South-East Asia journal of public health 2012
Santanu K Sharma Kanwar Narain Kangjam R Devi Padyumna K Mohapatra Rup K Phukana Jagadish Mahanta

Prevalence of anaemia among adolescent girl students of Assam, a north-eastern state of India, was evaluated along with its associating determinants. The present study revealed that anaemia is a major public health problem among adolescent girl students of Assam. The overall prevalence of anaemia among adolescent girl students of Assam is as high as 71.5%. Non-nutritional factors such as infect...

2017
Jill B. Brelsford Jordan L. Plieskatt Anna Yakovleva Amar Jariwala Brian P. Keegan Jin Peng Pengjun Xia Guangzhao Li Doreen Campbell Maria Victoria Periago Rodrigo Correa-Oliveira Maria Elena Bottazzi Peter J. Hotez David Diemert Jeffrey M. Bethony

A new generation of vaccines for the neglected tropical diseases (NTDs) have now advanced into clinical development, with the Na-GST-1/Alhydrogel Hookworm Vaccine already being tested in Phase 1 studies in healthy adults. The current manuscript focuses on the often overlooked critical aspects of NTD vaccine product development, more specifically, vaccine stability testing programs. A key measur...

Journal: :Geospatial health 2007
Giovanna Raso Penelope Vounatsou Donald P McManus Jürg Utzinger

There is growing interest in the use of Bayesian geostatistical models for predicting the spatial distribution of parasitic infections, including hookworm, Schistosoma mansoni and co-infections with both parasites. The aim of this study was to predict the spatial distribution of mono-infections with either hookworm or S. mansoni in a setting where both parasites co-exist. School-based cross-sec...

Journal: :Gastroenterology 2006
John Croese Marnie J Wood Wayne Melrose Richard Speare

BACKGROUND & AIMS Nearly 700 million people remain infected with hookworms. Although allergy is intuitively linked to immunity against helminths, few positive examples have been characterized. Larval migration through the lungs has been considered the likely interface at which hookworm attrition occurs. As part of a study evaluating a potential role for hookworms in the modulation of human auto...

Journal: :The Southeast Asian journal of tropical medicine and public health 1993
I M Bakta I D Widjana P Sutisna

Stool examination using direct smear method, Kato-Katz thick smear technique and modified Harada Mori test tube cultivation method were done on 2,331 people among the rural population of Bali. The serum ferritin was examined by ELISA technique and hemoglobin concentration by cyanmethemoglobin technique. Overall prevalence of hookworm infection was 24.02% with heterogeneity in local prevalences....

Journal: :PLoS Medicine 2005
Peter J Hotez Jeff Bethony Maria Elena Bottazzi Simon Brooker Paulo Buss

0187 Introduction In 1962, Norman Stoll, the distinguished Rockefeller Institute scientist who helped to establish human parasitology research in North America, described the unique health impact of hookworm as follows [1]: As it was when I fi rst saw it, so it is now, one of the most evil of infections. Not with dramatic pathology as are fi lariasis, or schistosomiasis, but with damage silent ...

2010
Maria Flavia Gazzinelli Lucas Lobato Leonardo Matoso Renato Avila Rita de Cassia Marques Ami Shah Brown Rodrigo Correa-Oliveira Jeffrey M. Bethony David J. Diemert

BACKGROUND Obtaining informed consent for clinical trials is especially challenging when working in rural, resource-limited areas, where there are often high levels of illiteracy and lack of experience with clinical research. Such an area, a remote field site in the northeastern part of the state of Minas Gerais, Brazil, is currently being prepared for clinical trials of experimental hookworm v...

Journal: :Southern Medical Journal 1920

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