Diencephalic syndrome is a rare condition associated with central nervous system tumors. The most common presentation is secondary failure to thrive with proper caloric intake and no statural impairment. Despite the importance of this syndrome, little is known of its pathophysiology. Some reports have documented changes in human growth hormone and insulin levels at the onset, whereas others hav...

BACKGROUND The multinational CHOICE (Contraceptive Health Research Of Informed Choice Experience) study evaluated the effects of structured counseling on women's contraceptive decisions, their reasons for making those decisions, and their perceptions of combined hormonal contraceptive (CHC) methods in eleven countries. The aim of this paper to present data from the 1,802 women participating in ...

Background: We aimed to assess the long-term toxic effects of sulphur mustard (SM) on the testis and male fertility two decades after exposure. Materials and Methods: A historical cohort study was conducted in 2005. Sixty-four SM-exposed and 64 matched SMunexposed casualties of the Iraq–Iran conflict were enrolled. Fecundity status, semen indices, hormonal assay results and testis histopatholog...

Women experience significant changes in iron status throughout their reproductive lifespans. While this is evident in regions with high rates of malnutrition and infectious disease, the extent of reproductive-related changes is less well known in countries with low rates of iron deficiency anemia, such as the United States. The goal of this study is determine the relationship between women's re...

BACKGROUND Following neoadjuvant chemotherapy (NACT) for breast cancer, changes in estrogen receptor (ER), progesterone receptor (PR), HER2 status, and Ki-67 index (IHC4 status) and its correlation with pathological complete response (pCR) or relapse-free survival (RFS) rates could lead to better understanding of tumor management. PATIENTS AND METHODS Pre- and post-NACT IHC4 status and its ch...

How is sexual conflict during reproduction resolved when parents collaborate to rear offspring? A new study shows that female burying beetles communicate their hormonal status to their male partners to avoid costly superfluous mating, using an anti-aphrodisiac pheromone.

PURPOSE We aimed to confirm the prognostic and predictive value of p53 expression, particularly in invasive breast cancer patients, according to immunohistochemical hormone receptor (HR) and human epidermal growth factor receptor 2 (HER2) status. METHODS Immunohistochemical data for p53, estrogen receptor, progesterone receptor, and HER2 expression from a total of 15,598 patients were retrosp...

background: atrazine (atr) is used as an agriculture herbicide worldwide. it has been shown that atr adversely affect the reproductive system in rodents. in this study we aimed to evaluate the impact of chronic exposure to atrazine (atr) on male testicular tissue, sperm parameters, serum level of total thiol molecules (ttm) and malodialdehyde (mda) content of testes. methods: to follow-up this ...