Cone-beam CT (CBCT) is being increasingly used in modern radiation therapy for patient setup and adaptive replanning. However, due to the large volume of x-ray illumination, scatter becomes a rather serious problem and is considered as one of the fundamental limitations of CBCT image quality. Many scatter correction algorithms have been proposed in literature, while a standard practical solutio...

Background: The human body contains of different tissues and cavities with different physical and radiological properties. Most important among these are tissues and cavities that are radiologically different from water, including lungs, sinuses and bones. Gel dosimetry provides a unique feature to display dose distributions occurring in clinical radiation therapy in three dimensions. Materials...

Ventilation distribution calculation using 4D CT has shown promising potential in several clinical applications. This study evaluated the direct geometric ventilation calculation method, namely the ΔV method, with xenon-enhanced CT (XeCT) ventilation data from four sheep, and compared it with two other published meth-ods, the Jacobian and the Hounsfield unit (HU) methods. Spearman correlation c...

Abstract Background To evaluate the predictive factors of urinary leakage (UL) following percutaneous nephrolithotomy (PNL) and to investigate relationship between Hounsfield unit (HU) stone UL. Methods We retrospectively reviewed data 728 patients who underwent PNL January 2012 2017. In total, 396 were eligible for study. Patient demographics, renal factors, properties operative details collec...

OBJECTIVE The VoxTox study, linking delivered dose to toxicity requires recalculation of typically 20-37 fractions per patient, for nearly 2000 patients. This requires a non-interactive interface permitting batch calculation with multiple computers. METHODS Data are extracted from the TomoTherapy(®) archive and processed using the computational task-management system GANGA. Doses are calculat...

BACKGROUND Idiopathic pulmonary fibrosis (IPF) is a severe and progressive respiratory disease with poor prognosis. Despite the positive outcomes from recent clinical trials, there is still no cure for this disease. Pre-clinical animal models are currently largely limited to small animals which have a number of shortcomings. We have previously shown that fibrosis is induced in isolated sheep lu...