نتایج جستجو برای: hpv18
تعداد نتایج: 577 فیلتر نتایج به سال:
Two hundred female sex workers (FSWs) in Lima, Peru were randomized to receive HPV4 vaccine in the standard (0, 2, 6 months) or a modified schedule (0, 3, 6 months). One hundred and eighty four (92%) participants completed 3 doses of vaccine. Baseline seropositive rates were 58% for HPV6, 22.5% for HPV11, 41.5% for HPV16, and 13% for HPV18. The final geometric mean antibody titer (GMT) followin...
In present studies, piezoelectric genesensors (PG) was in-house fabricated and then used to identify human papilloma viruses (HPV) in recurrent (22 samples) and original (22 samples) pathological biopsy specimens. PCR and associated dot blot hybridizations were both used to further confirm the results attained from PG instruments. Of the 22 recurrent specimens, 15 samples were positive for HPV6...
Human papillomavirus (HPV) DNAs are detected in approximately 90% of anogenital carcinomas. To assess directly the effect of HPV on squamous differentiation, normal human cervical and foreskin epithelial cells and cells immortalized by recombinant HPV DNAs were transplanted beneath a skin-muscle flap in athymic mice. Xenografts containing normal cells formed well-differentiated stratified squam...
Cervical cancer and its precursor intra-epithelial lesions are linked to infection by a subset of human papillomavirus (HPV) types, the so-called “high-risk” HPVs, the most prevalent being HPV16 and HPV18. Two prophylactic vaccines containing combinations of the major capsid protein (L1) of HPV16 and HPV18 have been shown to efficiently prevent infection by inducing capsid-specific neutralizing...
This study investigated possible variations in DNA damage in HeLa cells with silenced expression of the HPV/E6 oncogene compared with HeLa cells with normal expression of the E6 oncogene using the DNA breakage detection–fluorescence in situ hybridization (DBD–FISH) technique and a whole human genome DNA probe. The variable levels of DNA breaks present were measured quantitatively using image an...
BACKGROUND Limited data are available describing human papillomavirus (HPV) genotype distributions in cervical cancer in the United States. Such studies are needed to predict how HPV vaccination and HPV-based screening will influence cervical cancer prevention. METHODS We used the New Mexico Surveillance, Epidemiology, and End Results Registry to ascertain cases of in situ (n = 1213) and inva...
BACKGROUND The aim of this interim analysis of a large, international phase III study was to assess the efficacy of an AS04 adjuvanted L1 virus-like-particle prophylactic candidate vaccine against infection with human papillomavirus (HPV) types 16 and 18 in young women. METHODS 18,644 women aged 15-25 years were randomly assigned to receive either HPV16/18 vaccine (n=9319) or hepatitis A vacc...
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