breast metastasis of ovarian carcinoma is rare. to date, only 39 cases have been reported in the english-language  literature  so  far.  we  are  herewith  reporting  a  primary  ovarian  papillary  serous  cyst adenocarcinoma metastasing to breast and epsilateral supraclavicular node in a 58 year old female asthe first case in our centre, located at north-east india.  the purpose of reporting ...

Mucin 1 (MUC1) is a diagnostic factor and therapy target in lung adenocarcinoma. MUC1 C-terminal intracellular domain (CD) interacts with estrogen receptor (ER) a and increases gene transcription in breast cancer cells. Because lung adenocarcinoma cells express functional ERa and ERb, we examined MUC1 expression and MUC1–ER interaction. Because blocking MUC1 CD with an inhibitory peptide (PMIP)...

Landomycin E (LE) was recently isolated from Streptomyces globisporus strain 1912 and its chemical structure was studied. However, its biological activity is still poorly understood. We performed in vitro investigation of antitumor activity of this new member of the angucyclin family of antibiotics. Dose-dependent effect of LE on growth and survival of different tumor cell lines was studied in ...

Tubular Carcinoma (TC) of the breast, also known as tubular carcinoma or well-differentiated adenocarcinoma, is defined a special type breast cancer consisting structures with excellent prognosis by WHO (2019) pathological and genetic classification neoplasms. Two cases admitted to our hospital were reported. The relevant literature was reviewed clinical features, histological morphology (micro...

In the present study, we fabricated tungsten trioxide nanoparticles (WO3 NPs) from a complex [W(C13H10NO)3] of ligand N-salicylideneaniline with tungstic acid as precursor. Nanoparticles were synthesized using direct thermal decomposition method. These evaluated for cytotoxicity influence on human breast cancer MCF7 cell line (adenocarcinoma). The observed results suggested that WO3 can destroy...

In recent years, FLASH radiotherapy (FLASH RT) has gained attention in preclinical studies as a potential advancement cancer treatment. The great advantage of RT is the ultra-fast, high doses delivery that have similar or greater effect on cells while sparing normal, healthy tissue surrounding tumor site. This known effect. However, currently, there are not enough vitro and vivo data to transpo...

background: various mtt assay methods are proposed to obtain the cell sur- vival parameters. objective: determining the survival curve characteristics of two cancerous cells of interest based on a common and a novel mtt assay method after exposing them to ionizing radiation. method: a common and a novel mtt assay method were used and compared for obtaining the f10b16 melanoma and 4t1 breast ade...

The cytotoxicity of 27 benzanilides and dithiobenzanilides built on a stilbene scaffold and possessing various functional groups in aromatic rings previously described for their spasmolytic properties was assayed on three human cancer cell lines (A549 -lung adenocarcinoma, MCF-7 estrogen dependent breast adenocarcinoma and MDA-MB-231 estrogen independent breast adenocarcinoma) and 2 non-tumorig...

BACKGROUND A woman, mother of one at the age of 19 years, was diagnosed with mammary adenocarcinoma in the right breast in 1985 at the age of 37 years. The patient underwent surgery (quadrantectomy), lymphadenectomy and radiotherapy. In 1999, an adenocarcinoma was diagnosed in the left breast, followed by adequate resection, radiotherapy and anti-oestrogen receptor treatment for 6 years. In Mar...

Radiation therapy has a solid role in the management of breast adenocarcinoma. It significantly reduces the rates of disease recurrence. Nevertheless, radiation therapy is not without side effects and patients who have undergone breast irradiation are at increased risk for lung disease, sarcomas, acute leukemia and esophageal cancer. We present a case of radiation-induced breast osteosarcoma 29...