conclusions the high prevalence of hpv in abnormal cytology underlines to the fact that the presence of hpv is a critical factor in the development of cervical cancer. the use of hpv dna techniques could actually become an effective and fast means of ascertaining the presence of hpv in abnormal cytology. results result showed a 100% presence of high risk hpv in all the samples with abnormal cyt...

BACKGROUND Gastrointestinal (GI) malignancies are the most common cancers and account for nearly half of all cancer-related deaths in Iran. There was a strong association between human papillomavirus (HPV) infection and urogenital cancers, in particular the cervix. However, there is no clear causal relationship in all types of cancers, including gastrointestinal cancers. Therefore, the present ...

This study aims to evaluate human papillomavirus (HPV) prevalence and predominating genotypes in liquid-based cervical cytology samples from an Irish urban female population. In addition to use of routine cervical cytology testing, women are screened for HPV using the MY09/11 primers for the HPV L1 gene and primers for beta-globin amplification in a multiplex format. Overall, 996 women between ...

Background: Somatic TP53 mutations are frequent in head and neck squamous cell carcinoma (HNSCC) important pathogenic factors. Objective: To study relative to the presence of human papillomavirus (HPV) tumors HNSCC patients. Methods: Using a custom-made next-generation sequencing (NGS) panel on formalin-fixed, paraffin-embedded tumor tissue, we analyzed somatic single-nucleotide polymorphism (S...

This study evaluated the clinical performance of cobas 4800 HPV Test (Roche Molecular Systems, Pleasanton, CA, USA) for high-risk human papillomavirus (HR-HPV) testing with individual HPV-16/HPV-18 genotyping in women 21 years or older atypical squamous cells undetermined significance (ASCUS). Women (N = 47,208) were recruited United States during routine screening, and liquid-based cytology pe...

Introduction. Human papillomavirus 13 (HPV-13) belonging to Alphapapillomavirus-10 species, is an oral mucosotropic virus phylogenetically related others human (6, 11, 44, 55 and 74). It causes Multifocal Epithelial Hyperplasia, uncommon benign disease reported mainly amongst ethnic groups from America. Objective. To describe the genetic variability of HPV-13 L1 gene. Material Methods. A retros...

Human papilloma virus (HPV) is a DNA virus from the papillomavirus family that is capable of infecting humans. Like all papillomaviruses, HPVs establish productive infections only in keratinocytes of the skin or mucous membranes. While the majority of the known types of HPV cause no symptoms in most people, some types can cause warts (verrucae), while others can be in a minority of cases lead t...

The E2 proteins are transcription/replication factors from papillomaviruses. Human papillomaviruses (HPVs) can be broadly divided in two groups; low-risk HPV subtypes cause benign warts while high-risk HPVs give rise to cervical cancer. Although a range of crystal structures of E2 DNA-binding domains (DBD) from both high- and low-risk HPV subtypes have been reported previously, structures of E2...

BACKGROUND Human Papillomavirus (HPV) infection is considered the most prevalent sexually transmitted virus infection. Human Papillomavirus 16 and 18 have been documented as high-risk HPV infections and responsible for 70% of all cervical cancers. OBJECTIVES The aim of this study was to determine HPV genotypes in patients with anogenital warts. PATIENTS AND METHODS In this study lesion samp...