Human T-cell lymphotropic virus type I has been associated with adult T-cell leukemia and lymphoma, neurological disease (tropical spastic paraparesis or HTLV-I associated myelopathy) and, more recently, uveitis. This virus is highly endemic in some regions of the world, especially in southwest Japan, Caribbean islands, South America and parts of Central A frica1. The presence of HTLV-I/II in B...

recurrent spontaneous rupture of the urinary bladder has rarely been reported in english articles. this condition may be difficult to diagnosis before a laparotomy due to acute peritonitis. herein we describe a case of recurrent spontaneous rupture of the bladder in a 39-year-old woman with human t-lymphotropic virus type 1 (htlv-1) -associated myelopathy/topical spastic paraparesis (ham/tsp).

The type C retrovirus simian T-lymphotropic virus type III (STLV-III) has been isolated recently from immunodeficient macaque monkeys at the New England Regional Primate Research Center. The present studies were done to define the in vitro growth characteristics of this agent. STLV-III replicates efficiently in interleukin 2-dependent T-cell cultures of macaque peripheral blood lymphocytes (PBL...

The epidemiological characteristics of human T-cell lymphotropic virus type I infection in Taiwan have been explored by an island-wide community-based survey, which was carried out among residents in 19 townships and metropolitan precincts randomly selected through stratified sampling. Serum specimens of 7278 healthy subjects were screened by enzyme-linked immunosorbent assay and confirmed by W...

Short or damaged telomeres have been implicated in degenerative conditions. We hypothesized that analysis of telomere length (TL) in human T-cell lymphotropic virus (HTLV) infection and HTLV-associated neuropathy might provide clues to the etiology of HTLV-associated disease and viral dynamics. A subset of 45 human T-cell lymphotropic virus type 1 (HTLV-1), 45 human T-cell lymphotropic virus ty...

Human T-cell lymphotropic virus type I (HTLV-I) infection is associated with a variety of human diseases including HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP), a chronic progressive inflammatory neurological disease. An important risk factor for the development of HAM/TSP is thought to be a high HTLV-I proviral load. Histopathological studies have demonstrated the presen...