OBJECTIVE Oxygen therapy is used for the treatment of various diseases, but prolonged exposure to high concentrations of O(2) is also associated with formation of free radicals and oxidative damage. METHODS In the present study we compared alpha-ketoglutarate dehydrogenase (KGDH) activity and mitochondrial oxidative damage in the hearts of guinea pigs after long-term (17 and 60 h) oxygenation...

Oscillation in the bioluminescent intensity from a luminous bacteria suspension was observed. The time course of the luminescence intensity from a suspension containing luminous bacteria was measured. The oscillation mode changed with the liquid broth component. The optical density and dissolved oxygen (DO) concentration were measured simultaneously with the luminescence intensity, and a possib...

The recently discovered structural reconstruction in the cuprate superlattice (SrCuO2)n/(SrTiO3)2 has been investigated across the critical value of n = 5 using resonant inelastic x-ray scattering (RIXS). We find that at the critical value of n, the cuprate layer remains largely in the bulk-like two-dimensional structure with a minority of Cu plaquettes being reconstructed. The partial reconstr...

OBJECTIVE Neurological dysfunction remains a devastating postoperative complication in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB), and previous studies have shown that inhalation anaesthesia and total intravenous anaesthesia (TIVA) may produce different degrees of cerebral protection in these patients. Therefore, we conducted a systematic literature review and meta-an...

1. Technology Assessment Nitric Oxide inhalation (iNO) therapy is a noninvasive treatment for PPHN that involves inhalation of gaseous nitric oxide in conjunction with ventilator support. The potential of exogenous NO as a therapeutic agent is based on its potent vasodilator properties and its ability to be delivered as a gas to the lung. Exogenous NO increases the partial pressure of arterial ...