The objective of this study was to identify ERK 1/2 involvement in the changes in compressive and tensile mechanical properties associated with hydrostatic pressure treatment of self-assembled cartilage constructs. In study 1, ERK 1/2 phosphorylation was detected by immunoblot, following application of hydrostatic pressure (1 h of static 10 MPa) applied at days 10-14 of self-assembly culture. I...

Four strains of euryhaline bacteria belonging to the genus Halomonas were tested for their response to a range of temperatures (2, 13, and 30 degrees C), hydrostatic pressures (0.1, 7.5, 15, 25, 35, 45, and 55 MPa), and salinities (4, 11, and 17% total salts). The isolates were psychrotolerant, halophilic to moderately halophilic, and piezotolerant, growing fastest at 30 degrees C, 0.1 MPa, and...

The adult respiratory distress syndrome (ARDS) is almost invariably accompanied by permeability pulmonary oedema, usually appearing in the first few hours [1, 2]. The extent and therefore the seriousness of this oedema is proportional to the filtration of fluid and proteins through the pulmonary vascular endothelium. The extreme sensitivity of this filtration to variations of capillary pressure...

objective: this study examines the effects of hydrostatic pressure on in vitro maturation (ivm) of oocytes derived from in vitro grown follicles. materials and methods: in this experimental study, preantral follicles were isolated from 12-day-old female nmri mice. each follicle was cultured individually in alpha minimal essential medium (α-mem) under mineral oil for 12 days. then, follicles wer...

we present a case of infantile intussusception treated successfully using hydrostatic reduction, highlighting the importance of non-surgical techniques as the first line of management for this entity. physicians should strive for mastery over such techniques by extensive training to prevent unwanted surgical procedures in such cases.

Mechanical forces can influence the structure and development of healthy cancerous cells tissue microenvironments, acting on their physical shape promoting non-genetic alterations during growth. For this reason, it is interesting to investigate role dynamic hydrostatic compression such cultures, assess stimuli key parameters, as cell differentiation, stiffness cytoskeleton rearrangements. In wo...

It is generally known that severe plastic deformation processes with back pressure not only apply higher hydrostatic stress and more deformation compared to what a regular process can apply to a workpiece but also prevent surface defects in the workpiece during the process. Hydrostatic cyclic expansion extrusion (HCEE) was developed recently for processing long ultrafine-grained metals and allo...

In many filamentary structures, such as hydrostatic arms, roots, and stems, the active or growing part of material depends on contractile elongating fibers. Through their activation by muscular contraction growth, these fibers will generate internal stresses that are partially relieved filament acquiring intrinsic torsion curvature. This process is fundamental in morphogenesis but also plant tr...

The high-pressure structural chemistry of α-zirconium phosphate, α-Zr(HPO4)2·H2O, was studied using in-situ high-pressure diffraction and synchrotron radiation. The layered phosphate was studied under both hydrostatic and non-hydrostatic conditions and Rietveld refinement carried out on the resulting diffraction patterns. It was found that under hydrostatic conditions no uptake of additional wa...