Chitosan/hydroxyapatite-based composites. In the past 20 years, there has been a growing trend towards the development and use of biomaterials for the repairing and restoration of damaged bone tissue. The calcium phosphate bioceramics have received great attention in the field of orthopaedics because of its similarity to the mineral component of bone tissue. They have been used as granules in n...

Background and purpose - [18F]Fluoride ([18F]NaF) PET scan is frequently used for estimation of bone healing rate and extent in cases of bone allografting and fracture healing. Some authors claim that [18F]NaF uptake is a measure of osteoblastic activity, calcium metabolism, or bone turnover. Based on the known affinity of fluoride to hydroxyapatite, we challenged this view. Methods - 10 male r...

The present study compares the biologic behavior of BioGran and Calcitite as fillers for surgical cavities in the mandibles of 4 adult monkeys (Cebus apella). The surgical cavities were prepared through both mandibular cortices, with a diameter of 5 mm, in the angle region. Two cavities were prepared on the right side and 1 on the left and divided into 3 groups: R1 sites were filled with biogla...

OBJECTIVE To assess middle ear aeration after total mastoid obliteration using bone pate and hydroxyapatite performed at the second stage of intact-canal-wall (ICW) tympanoplasty. STUDY DESIGN Retrospective study. SETTING Tertiary referral hospital. PATIENTS Forty-two ears with cholesteatoma underwent the obliteration. Computed tomography (CT) scan 1 week before the second-stage operation...

The present work focuses on the physicochemical characterization of selected mineral-based biomaterials that are frequently used in dental applications. The selected materials are commercially available as granules from different biological origins: bovine, porcine, and coralline. Natural and calcined human bone were used for comparison purposes. Besides a classical rationalization of chemical ...

Abstract Although the initial in vitro dissolution of bioactive glasses (BAG) is well characterized, long-term behaviour crystallized BAG scaffolds a continuous fluid flow incompletely understood. A detailed understanding vital for predicting their clinical applications. Here, we explored and reaction mechanisms partly crystalline glass–ceramic based on S53P4 45S5 using flow-through method Tris...

UNLABELLED In the present case of postoperative lumbar spinal stenosis after non-instrumented intertransverse fusion with granules of hydroxyapatite (HA), bone union was not completed and the patient felt the recurrence of his symptoms within two years. We performed re-decompression with fusion, and in hematoxylin and eosin staining of HA granulation harvested during revision surgery, fibrous t...

Addition of hydroxyapatite (HyAp) microcrystals to human neutrophils results in exocytosis of specific granules, measured as lysozyme release, and plasma membrane damage, evident from lactate dehydrogenase (LDH) release. The strong hydrogen acceptor polyvinylpyridine-N-oxide has no effect on enzyme release, but polyanions and negatively charged proteins such as albumin strongly inhibit HyAp ind...