The amide-linked local anesthetics can be used safely in patients susceptible to malignant hyperthermia (MH). 4-Hydroxybenzoic acid methyl ester contained as a preservative in local anesthetic solution was suspected to have triggered MH in a patient who had received nerve block with lidocaine solution. The author investigated the effects of 4-hydroxybenzoic acid methyl ester on Ca(2+)-related f...

In this paper, the extraction of polyphenols from amaranth seed using a Box–Benhken design four factors—ultra-turrax speed, solid-to-liquid ratio (RSL), methanol concentration and time—were studied. There were two responses studied for model: total phenolic content (TPC) flavonoid (TFC). The factors which influenced most TPC TFC RSL, ultra-turrax speed. Twelve acids (rosmarinic acid, p-coumaric...

The potentiality of different phenolic compounds, belonging to both hydroxycinamic (caffeic, sinapinic and ferulic acids) and hydroxybenzoic (protocatechuic, syringic and vanillic acids) families to generate different gold nanoparticles (AuNPs) has been investigated. The synthesized AuNPs were characterized by transmission electron microscopy (TEM) andUV-Vis absorption spectroscopy. The influen...

An analytical method for the quantitative determination of the principal phenolic compounds (benzoic acids, hydroxycinnamic acids, 3-phenylpropionic acids, flavanols, procyanidins, dihydrochalcones, quercetin glycosides) in ciders, which successfully employs a RP-HPLC and photodiode-array detection system without prior treatment of the sample, is described. Parameters usually examined in the me...

Abstract: New mono acid esters have been synthesized from the reaction of benzoic acid and mono-hydroxybenzoic acids with 2-phenoxyethanol separated from Urtica pilulifera, characterized, and screened for possible antioxidant, antifungal, antimicrobial and anticancer activities. These phenolic acid esters gave various degrees of free radical scavenging, but the values were lower than that of α-...

Abstract: New mono acid esters have been synthesized from the reaction of benzoic acid and mono-hydroxybenzoic acids with 2-phenoxyethanol separated from Urtica pilulifera, characterized, and screened for possible antioxidant, antifungal, antimicrobial and anticancer activities. These phenolic acid esters gave various degrees of free radical scavenging, but the values were lower than that of α-...

in this study, we investigate the potential of moricandia arvensis methanol leaf extract (meohl) on calpain activity, melanin biosynthesis and dna mutagenicity. cytotoxic effect and measurement of reactive oxygen species (ros) induced by lucigenin in colorectal cells (be) were also determined. in addition the chemical analysis of the extract was also studied and the chemical profile illustrates...

Lentinus crinitus is a wild fungus, which produces mushrooms consumed by some Amazonian Indians. Besides, it recognized for its diverse biological activities and biotechnological applications. However, there are few reports with limited information on basidiocarp chemical composition cytotoxicity. Our study determined evaluated the composition, cytotoxicity, antioxidant activity of L. pileus st...

The aim of this work was to investigate the effect of phenolic acids on cell membrane permeability of lactic acid bacteria from wine. Several phenolic acids were tested for their effects on the cell membrane of Oenococcus oeni and Lactobacillus hilgardii by measuring potassium and phosphate efflux, proton influx and by assessing culture viability employing a fluorescence technique based on memb...