BACKGROUND Urinary albumin excretion frequently persists in diabetic patients who are treated with angiotensin-converting enzyme inhibitors (ACEI) or angiotensin receptor blockers (ARB). Sulodexide, a glycosaminoglycan mixture of 80% heparan sulfate and 20% dermatan sulfate, has been hypothesized to reduce persistent albuminuria. We have conducted a multi-center randomized double-blind pilot st...

The potent induction of hepatic cytochrome P450 3A isoforms by rifampin complicates therapy for coinfection with human immunodeficiency virus (HIV) and Mycobacterium tuberculosis. We performed an open-label, single-arm study to assess the safety and pharmacokinetic interactions of the HIV protease inhibitor atazanavir coadministered with rifampin. Ten healthy HIV-negative subjects completed pha...

the present study was conducted to examine the effects of essential oil satureja hortensis l. on antifungal properties in feed staff using an in vitro system. for this purpose, the samples of feed stuff sterilized in an autoclave and then were added 2 ml of spore aspergillus flavus to each sample (300 g of feed stuff). the amount 3 ml of different concentration of essential oil (0, 300, 400, 50...

An experiment was conducted using a total of 420, 1-d-old, Arbor Acres commercial male chicks to compare copper sulfate and tribasic copper chloride (TBCC) as sources of supplemental copper for broilers. Chicks were randomly allotted to 1 of 7 treatments for 6 replicates of 10 birds each and were fed a basal corn-soybean meal diet (11.45 mg/kg copper) supplemented with 0, 150, 300, or 450 mg/kg...

The acute toxicity of sulfate to Ceriodaphnia dubia, Chironomus tentans, Hyalella azteca, and Sphaerium simile was assessed to support potential updates of Illinois (USA) sulfate criteria for the protection of aquatic life. The mean lethal concentrations to 50% of a sample population (LC50s), expressed as mg S04(-2)/L, in moderately hard reconstituted water (MHRW) were as follows: 512 mg/L for ...

The medicinal plant Olea europaea L. is a valuable one whose fruit and its oil are considered as food. There are some reports in ancient medical literature that aqueous extract of its leaves has analgesic effects. This prompted us to investigate the analgesic effect of aqueous extract of its leaves using formalin and tail-flick tests. For this purpose, male NMRI rats weighting 220-260 g were us...

the present study is a designed protocol for investigation of the analgesic effect of oral and intraperitoneal (i.p.) administration of alcoholic datura stramonium (ds) seed extract as a rich source of alkaloid substances. male nmri rats were divided into control and treatment groups. the treatment rats received different doses of the ds seed extract, which was prepared from alcoholic smashed s...

The universality of inhibitors is understood as their ability to inhibit several types corrosion attack: hydrogen sulfide and carbon dioxide corrosion, diffusion into metal, development sulfate-reducing other bacteria, negative impact on the mechanical properties metals. Indicators universalism new inhibitor have been studied. Producer inhibiting compositions Limited Liability Company «INCORGAZ...

Tetrabromobisphenol A (TBBPA) is widely used as a flame retardant and is suspected to be stable in the environment with possible widespread human exposures. This study reports the characterization of the toxicokinetics of TBBPA in human subjects and in rats. A single oral dose of 0.1 mg/kg TBBPA was administered to five human subjects. Rats were administered a single oral dose of 300 mg TBBPA/k...